5-Bromo-2-ethoxypyridine

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Comprehensive Guide to 5-Bromo-2-ethoxypyridine

Table of Contents

1. Product Overview & Specifications

5-Bromo-2-ethoxypyridine (CAS 76041-72-4) is a halogenated pyridine derivative widely used in pharmaceutical and agrochemical synthesis.

Parameter Specification Comparison with 5-Bromo-2-methoxypyridine
Molecular Formula C7H8BrNO Same core structure
Molecular Weight 202.05 g/mol +14.03 g/mol vs methoxy analog
Purity ≥98% (HPLC) Comparable purity levels
Boiling Point 265-268°C Higher thermal stability

2. Key Applications

Pharmaceutical Intermediates

Critical building block for:

  • Kinase inhibitor development
  • Antiviral drug candidates
  • Central nervous system (CNS) therapeutics

Agrochemical Synthesis

  • Herbicide precursors
  • Fungicide formulation components

Material Science

  • Coordination complexes for catalysis
  • Ligand design for transition metal complexes

3. Usage Scenarios

Suzuki-Miyaura Cross-Coupling

Typical reaction conditions:

Parameter Value
Catalyst Pd(PPh3)4 (5 mol%)
Solvent DME/H2O (3:1)
Yield 82-89%

4. Client Success Stories

PharmaSynth Inc. (USA)

Challenge: Required high-purity intermediate for Phase II clinical trial material
Solution: Supplied 50kg GMP-grade material with 99.7% purity
Outcome: Successful API production meeting FDA requirements

AgroChem Solutions GmbH (Germany)

Challenge: Needed stable halogen source for novel herbicide
Solution: Custom synthesis with enhanced solubility profile
Result: 23% improvement in field efficacy

5. Request Product Information

Contact our technical team for custom synthesis options:

Key advantages of partnering with us:

  • Batch-to-batch consistency
  • Technical support throughout R&D phases
  • Global logistics network
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