3-BROMO-2-HYDROXY-6-PICOLINE

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Comprehensive Guide to 3-Bromo-2-Hydroxy-6-Picoline

Table of Contents

Product Overview & Key Specifications

Parameter 3-Bromo-2-Hydroxy-6-Picoline Similar Compounds
CAS Number 1197191-23-1 Varies by derivative
Molecular Formula C6H5BrNO Depends on substituents
Purity >98% (HPLC) Typically 95-99%
Storage Conditions 2-8°C in inert atmosphere Room temp for stable analogs

Applications in Pharmaceutical & Chemical Industries

Pharmaceutical Intermediate: Critical precursor for kinase inhibitors in oncology treatments.

Agrochemical Synthesis: Building block for novel pesticide formulations with improved environmental profiles.

Coordination Chemistry: Chelating agent for transition metal catalysts in asymmetric synthesis.

Usage Guidelines & Best Practices

Handling Protocol: Always use under nitrogen atmosphere due to sensitivity to moisture and oxygen.

Reaction Optimization: Recommended molar ratio 1:1.2 with coupling partners in cross-coupling reactions.

Purification Methods: Column chromatography (silica gel, ethyl acetate/hexane) yields optimal results.

Case Studies: Real-World Implementations

Case 1: Synthesis of Bruton’s Tyrosine Kinase (BTK) Inhibitor

Used as key intermediate in 7-step synthesis achieving 62% overall yield

Case 2: Development of OLED Electron Transport Materials

Enabled 15% improvement in device lifetime through optimized coordination complexes

Client Success Stories

PharmaCorp Inc. (USA):

  • Reduced lead compound synthesis time from 14 to 8 days
  • Achieved 99.2% purity in final API batches

AgroSolutions GmbH (Germany):

  • Developed 3 novel fungicides with 40% improved efficacy
  • Passed OECD 301F biodegradability testing

Request Customized Quotation

Contact our technical team for batch-specific analytical data and volume pricing:

Email: info@vivalr.com

Tel: (86) 15866781826

Available in quantities from 100mg to kilogram scale. Custom synthesis and stable isotope-labeled versions available.

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