5-FLUORO-8-HYDROXYQUINOLINE: Comprehensive User Guide
Table of Contents
- 1. Product Specifications & Comparative Analysis
- 2. Key Applications & Industrial Uses
- 3. Operational Best Practices
- 4. Case Studies & Implementations
- 5. Client Success Stories
- 6. Request Customized Solutions
1. Product Specifications & Comparative Analysis
| Parameter | 5-Fluoro-8-Hydroxyquinoline | 8-Hydroxyquinoline | 5-Chloro-8-Hydroxyquinoline |
|---|---|---|---|
| CAS Number | 607-24-7 | 148-24-3 | 130-16-5 |
| Molecular Formula | C9H6FNO | C9H7NO | C9H6ClNO |
| Purity Grade | ≥98% (HPLC) | ≥95% | ≥97% |
| Melting Point | 228-232°C | 74-76°C | 192-194°C |
2. Key Applications & Industrial Uses
Pharmaceutical Intermediate: Critical component in synthesizing quinolone antibiotics with enhanced antimicrobial activity against Gram-positive bacteria.
Metal Chelation: Superior binding capacity for transition metals (Cu²⁺, Fe³⁺) compared to non-fluorinated analogs in industrial catalysts.
Analytical Chemistry: Fluorescent probe for aluminum ion detection with detection limit of 0.1 μM in environmental monitoring.
3. Operational Best Practices
Storage: Maintain in amber glass containers at 2-8°C under nitrogen atmosphere to prevent oxidative degradation.
Handling: Use PPE including neoprene gloves and chemical goggles due to potential skin/eye irritation (LD50 oral rat: 320 mg/kg).
Solubility Optimization: Achieve 25 mg/mL in ethanol:water (7:3 v/v) mixtures at 40°C with ultrasonic assistance.
4. Case Studies & Implementations
Case 1: European API manufacturer increased antibiotic yield by 18% through fluorinated quinoline intermediates in ciprofloxacin synthesis.
Case 2: Japanese electronics firm developed novel OLED materials using metal-chelate complexes with 15% improved luminescence efficiency.
5. Client Success Stories
Client A: Top 10 Pharma Company (USA) reduced synthetic steps from 7 to 4 in new antibacterial drug development using our GMP-grade material.
Client B: German Research Institute created advanced wastewater treatment system with 99.2% heavy metal removal efficiency.
Client C: Asian Agrochemical Leader developed next-gen fungicide with 40% lower application rates through fluorinated active components.
6. Request Customized Solutions
Contact our technical team for:
- Bulk pricing (100kg+ orders)
- Custom synthesis (purity 98-99.9%)
- Regulatory support (REACH, FDA DMF)
Email: info@vivalr.com
Tel: (86) 15866781826


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