2-CHLOROISONICOTINAMIDE

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Comprehensive Guide to 2-Chloroisonicotinamide: Applications, Case Studies, and Procurement

Table of Contents

1. Product Overview & Specifications

2-Chloroisonicotinamide (CAS 100779-96-6) is a halogenated pyridine derivative widely used in pharmaceutical and agrochemical synthesis. Key specifications:

Parameter Specification Competitor A Competitor B
Purity ≥98% ≥97% ≥95%
Appearance White crystalline powder Off-white powder Yellowish crystals
Solubility Soluble in DMSO, DMF Partial solubility Limited data

2. Key Applications

Primary industrial uses include:

  • Pharmaceutical Intermediate: Synthesis of kinase inhibitors (e.g., EGFR inhibitors)
  • Agrochemical Production: Building block for fungicides and herbicides
  • Chemical Research: Ligand in catalytic reactions

3. Industry Case Studies

Case 1: Anticancer Drug Development

Client: Top 10 Global Pharma Company (Confidential)
Application: Used in 6-step synthesis of investigational ALK inhibitor
Outcome: 22% yield improvement vs. previous intermediates

Case 2: Crop Protection Formulation

Client: European Agrochemical Manufacturer
Application: Key component in next-gen fungicide
Result: Achieved 99.2% purity for GLP toxicity studies

4. Procurement Guidance

Critical considerations for buyers:

Factor Recommendation
Batch Consistency Request COA with HPLC chromatograms
Regulatory Compliance Verify DMF/CEP status for pharma use
Packaging Prefer nitrogen-sealed amber glass bottles

5. Request Custom Quote

Contact our technical team for bulk pricing or sample requests:

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