5-CHLORO-2-HYDROXYPYRIMIDINE: Comprehensive Product Guide
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications
- 3. Usage Scenarios
- 4. Industry Case Studies
- 5. Request Quotation
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 22129-87-7 |
| Molecular Formula | C4H3ClN2O |
| Molecular Weight | 130.53 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% (HPLC) |
| Storage | 2-8°C in dry container |
Comparative Analysis
| Feature | 5-Chloro-2-hydroxypyrimidine | 2-Hydroxypyrimidine | 5-Bromo-2-hydroxypyrimidine |
|---|---|---|---|
| Reactivity | High nucleophilic substitution potential | Moderate | Excellent for coupling reactions |
| Pharma Applications | Antiviral intermediates | Limited | Oncological compounds |
2. Key Applications
This heterocyclic compound serves as:
- Building block for nucleotide analogs in antiviral drugs
- Intermediate in agrochemical synthesis (herbicides/pesticides)
- Ligand precursor in catalytic systems
3. Usage Scenarios
Pharmaceutical Synthesis
Used in 3-step synthesis of Remdesivir analogs through chlorination and glycosylation.
Agrochemical Production
Key intermediate in pyrimidine-containing fungicides with 85-92% yield in coupling reactions.
4. Industry Case Studies
Case 1: Antiviral Drug Development
Client: Top 10 Global Pharma Company
Application: Nucleoside analog synthesis
Result: Achieved 40% faster reaction kinetics vs. bromo derivatives
Case 2: Novel Insecticide Formulation
Client: EU Agrochemical Manufacturer
Application: Chlorinated pyrimidine core structure
Result: 30% cost reduction in production scale-up
5. Request Quotation
Contact our technical team for:
- Batch-specific COA
- Custom synthesis options
- Bulk pricing (25kg+ quantities)
Email: info@vivalr.com
Tel: (86) 15866781826


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