3-ACETYL-2-CHLOROPYRIDINE

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3-Acetyl-2-Chloropyridine: Technical Specifications

Chemical Profile

Parameter Specification
CAS Number 54240-34-7
Molecular Formula C7H6ClNO
Purity >99% (HPLC)
Appearance White to off-white crystalline powder
Storage 2-8°C in airtight container

Competitive Comparison

Feature Our Product Generic Alternatives
Purity Level 99.5% 95-98%
Byproduct Content <0.3% 1-2%
Stability 24-month shelf life 12-18 months

Core Applications in Modern Chemistry

Pharmaceutical Intermediates

Critical component in synthesizing:

  • Atypical antipsychotics (e.g., Iloperidone analogs)
  • Antiviral prodrugs
  • Kinase inhibitor precursors

Agrochemical Development

Key building block for:

  • Neonicotinoid alternatives
  • Fungicidal carboxamides
  • Plant growth regulators

Optimized Usage Protocols

Pharmaceutical Synthesis

Recommended conditions for Buchwald-Hartwig amination:

Parameter Optimal Value
Catalyst Pd(dba)₂/XPhos
Temperature 110-120°C
Reaction Time 18-24 hours

Scale-Up Considerations

  • Maintain N₂ atmosphere during transfers
  • Use anhydrous DMF as preferred solvent
  • pH stabilization between 6.8-7.2

Client Implementation Cases

Case 1: European Pharma Innovator

Challenge: Scale-up bottleneck in antipsychotic API production
Solution: Optimized 3-step synthesis using our material
Results: 22% yield improvement, 98.7% API purity

Case 2: Asian Crop Science Leader

Challenge: Developing resistance-breaking fungicide
Solution: Customized particle size distribution (D90 < 50μm)
Results: 40% efficacy increase against Fusarium species

Technical Consultation & Ordering

Available configurations:

  • Research quantities: 25g-5kg
  • GMP-grade batches: 10-100kg
  • Customized packaging solutions

Contact our chemists:
Email: info@vivalr.com
Tel: (86) 15866781826

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