2-Amino-5-nitro-4-picoline: Technical Guide for Industrial Applications
Table of Contents
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 2-Amino-5-nitro-4-picoline |
| CAS Number | 21901-40-6 |
| Molecular Formula | C6H7N3O2 |
| Molecular Weight | 153.14 g/mol |
| Appearance | Yellow crystalline powder |
| Purity Grade | Industrial (≥98%) |
2. Key Applications & Functional Properties
Core Applications:
- Pharmaceutical intermediates for antimalarial drugs
- Precursor in agrochemical synthesis
- Dye manufacturing intermediate
- Coordination chemistry applications
Functional Advantages:
- High reactivity in nitro-group transformations
- Thermal stability up to 180°C
- Solubility in polar aprotic solvents
3. Industrial Use Cases
Case Study 1: Antiparasitic Drug Synthesis
Used as critical intermediate in production of antiparasitic compounds through nucleophilic substitution reactions. Enables 32% yield improvement compared to traditional pathways.
Case Study 2: Specialty Dye Manufacturing
Key component in synthesis of azo dyes for textile industry, providing enhanced color fastness and UV stability in final products.
4. Synthesis & Quality Control
Manufacturing Process:
- Nitration of 2-amino-4-picoline precursor
- Controlled sulfonation reaction
- Multi-stage purification process
QC Parameters:
| Test | Method | Spec |
|---|---|---|
| Assay | HPLC | ≥98% |
| Residual Solvents | GC | <500 ppm |
5. Safety Protocols & Handling
Hazard Classification:
- Acute Toxicity (Category 3)
- Skin Corrosion (Category 1B)
PPE Requirements:
- Chemical-resistant gloves (Butyl rubber)
- Full-face respirator with organic vapor cartridge
- Impervious protective clothing
First Aid Measures:
| Exposure Route | Response Protocol |
|---|---|
| Inhalation | Immediate removal to fresh air, administer oxygen if needed |
| Skin Contact | Flush with water for 15 minutes, remove contaminated clothing |
6. Technical Inquiry Guidance
For customized specifications or bulk pricing:
- Email: info@vivalr.com
- Tel: (86) 15866781826 (24/7 technical support)
Request the following when inquiring:
- Required quantity (kg/Ton)
- Packaging specifications
- Target application details


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