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3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Chemical Name: 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS Number: [Insert CAS] | Molecular Formula: C₁₁H₁₄ClN₃O
Molecular Weight: 239.7 g/mol | Purity: ≥98% (HPLC)
Comparative Analysis
| Parameter | This Product | Similar Compounds |
|---|---|---|
| Synthetic Yield | 82-85% | 70-75% |
| Stability | 24 months at -20°C | 12-18 months |
| Solubility | DMSO, Ethanol | Limited in DMSO |
2. Key Applications
This potent kinase inhibitor intermediate is widely used in:
- Oncology Research: Targets PI3K/AKT/mTOR pathways for cancer drug development
- Anti-inflammatory Agents: Modulates TLR4 signaling in autoimmune disease studies
- Neurological Studies: Crosses blood-brain barrier for Alzheimer's research
3. Usage Case Studies
Case 1: Enhanced Drug Efficacy
A research team achieved 40% higher bioavailability in kinase inhibitors by using this compound as a precursor compared to traditional intermediates.
Case 2: Scalability Success
Pharma manufacturer reduced synthesis steps from 7 to 4 using our product, cutting production costs by 32%.
4. Client Success Stories
ABC Pharmaceuticals (Shanghai)
Challenge: Needed stable intermediate for PI3Kδ inhibitor development
Solution: Used 50kg batch with 99.2% purity
Result: Accelerated preclinical trials by 6 months
EuroBio Research (Berlin)
Challenge: Required low-impurity compound for CNS drug R&D
Solution: Custom synthesis with ≤0.5% impurities
Result: Achieved 90% target engagement in animal models
5. Request a Quote
Contact our technical team for:
- Custom synthesis options
- Bulk pricing (1kg+ orders)
- MSDS & regulatory support
Email: info@vivalr.com
Phone: (86) 15866781826
