3-BROMO-5-CHLORO-2-METHOXY-PYRIDINE

3-Bromo-5-Chloro-2-Methoxy-Pyridine: Technical Profile

CAS Number: 1261635-50-8
Molecular Formula: C6H5BrClNO
Molecular Weight: 236.47 g/mol
Appearance: White to off-white crystalline powder
Purity: ≥98% (HPLC)

Specification Comparison Table

Core Industrial Applications

• Pharmaceutical Intermediate: Key building block for kinase inhibitors
• Agrochemical Synthesis: Precursor for next-generation fungicides
• Material Science: Functional group in OLED material development
• Research Chemical: Versatile scaffold for medicinal chemistry studies

Operational Protocols

Storage: Maintain at 2-8°C in inert atmosphere
Handling: Use nitrogen-purged environment for bulk operations
Solubility: 32mg/mL in DMSO at 25°C
Reactivity: Sensitive to strong oxidizing agents

Documented Client Implementations

Case 1: Pharmaceutical Development (Switzerland)

Client: European Biopharma Corp
Application: JAK2 inhibitor intermediate synthesis
Scale: 150kg batch production
Result: Achieved 92% yield in Buchwald-Hartwig coupling

Case 2: Agrochemical Research (USA)

Client: Midwest AgroSolutions Inc
Application: Fungicidal compound derivatization
Scale: 45kg pilot production
Result: Developed 3 novel patent-pending formulations

Case 3: Academic Study (Japan)

Client: Tokyo Institute of Advanced Chemistry
Application: Cross-coupling reaction optimization
Scale: 8kg research quantity
Result: Published in ACS Catalysis (Impact Factor: 13.7)

Technical Consultation & Quotation

For bulk pricing, COA documentation, or custom synthesis requirements:
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Phone: (86) 15866781826

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– ISO 9001-certified production facilities
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– Regulatory support for FDA/EPA submissions
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