2-Chloro-4-bromopyridine

Table of Contents

1. Basic Information & Specifications
2. Key Applications
3. Usage Case Studies
4. Client Implementation Examples
5. Request Quotation

1. Basic Information & Specifications

Chemical Profile

Comparative Analysis

2. Key Applications

Pharmaceutical Intermediates

Preferred building block for:

• Tyrosine kinase inhibitor precursors
• Anticancer drug candidates (EGFR/VEGFR inhibitors)
• Neurological disorder therapeutics

Agrochemical Synthesis

• Neonicotinoid insecticide intermediates
• Fungicide active ingredient development
• Herbicide metabolite studies

3. Usage Case Studies

Case 1: Antineoplastic Drug Development

Used in 7-step synthesis of third-generation ALK inhibitor (patent WO2021156478A1), achieving 92% yield in Buchwald-Hartwig amination.

Case 2: Novel Pesticide Formulation

Key intermediate in EPA-registered insecticide requiring bromine-chlorine synergy for enhanced pest nervous system targeting.

4. Client Implementation Examples

Pharma Client: BioGenix Therapeutics

• Annual Consumption: 850kg
• Application: NSCLC treatment API synthesis
• Purity Requirement: 99.5% (cGMP standards)

Agro Client: CropShield AG

• Usage: Soil-stable insecticide production
• Scale: 12 metric tons/year
• Technical Requirement: ≤0.5% residual solvents

5. Request Quotation

Contact our technical team for:

• Custom synthesis options
• Bulk pricing (100kg+ orders)
• Regulatory support documentation

Email: info@vivalr.com
Tel: (86) 15866781826