Parameter | 3-Amino-2-picoline | Comparable Compounds |
---|---|---|
CAS Number | 3430-10-2 | 1603-40-3 (2-Amino-3-picoline) |
Molecular Formula | C6H8N2 | C6H8N2 |
Molecular Weight | 108.14 g/mol | 108.14 g/mol |
Synonyms | 2-Methyl-3-aminopyridine | 3-Methyl-2-aminopyridine |
Key Differentiation: Unique methyl group positioning enhances reactivity in pharmaceutical synthesis compared to structural isomers.
Used as critical building block in HIV protease inhibitor production through nucleophilic substitution reactions.
Serves as chelating agent in glyphosate derivatives, enhancing herbicidal activity by 15-20% compared to traditional analogs.
Challenge: Required scale-up from lab to 500kg batches while maintaining ≤0.5% impurities
Solution: Custom purification protocol development
Outcome: Achieved 99.3% purity with 22% cost reduction
Challenge: Needed stable precursor for temperature-sensitive formulations
Solution: Modified synthesis pathway with inert gas protection
Outcome: 98% yield at 40°C operation
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