2,6-DICHLORO-4-HYDROXYPYRIDINE

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2,6-Dichloro-4-hydroxypyridine: Technical Guide & Applications

Table of Contents

1. Product Overview & Specifications

2,6-Dichloro-4-hydroxypyridine (CAS 17372-52-8) is a halogenated pyridine derivative widely used in pharmaceutical synthesis and agrochemical intermediates.

Parameter Specification
Molecular Formula C5H3Cl2NO
Molecular Weight 178.99 g/mol
Appearance White to off-white crystalline powder
Purity ≥98% (HPLC)
Solubility Soluble in DMSO, methanol; slightly soluble in water

2. Key Applications & Use Cases

Pharmaceutical Intermediates

  • Antibiotic synthesis: Key precursor for cephalosporin-class antibiotics
  • Antifungal agents: Building block for triazole derivatives

Agrochemical Uses

  • Herbicide intermediates: Chlorinated pyridine structures in crop protection
  • Fungicide development: Bioactive component in systemic fungicides

3. Industrial vs. Pharmaceutical Grade Comparison

Feature Industrial Grade Pharmaceutical Grade
Purity 95-98% ≥99.5%
Heavy Metals <50 ppm <10 ppm
Price Range $120-$150/kg $400-$600/kg

4. Customer Case Studies

Case 1: Antibiotic Manufacturer (India)

  • Challenge: Improve yield in cefepime intermediate synthesis
  • Solution: Optimized 2,6-Dichloro-4-hydroxypyridine purification process
  • Result: 22% yield increase, 99.3% API purity achieved

Contact for technical details: info@vivalr.com

Case 2: Agrochemical Company (Germany)

  • Challenge: Develop low-residue fungicide for EU market
  • Solution: Custom chlorination protocol for pyridine derivatives
  • Result: 40% reduction in application concentration, passed REACH compliance

5. Request Customized Solutions

Our technical team provides:

  • GMP-certified synthesis
  • Batch-specific analytical reports
  • Regulatory support (FDA DMF, CEP available)

Contact: info@vivalr.com | Tel: (86) 15866781826

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