2-Chloropyridine-4-boronic acid pinacol ester

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2-Chloropyridine-4-boronic acid pinacol ester: Comprehensive User Guide

Table of Contents

1. Product Overview & Specifications

CAS Number: 1072951-39-0
Molecular Formula: C11H14BClNO2
Molecular Weight: 239.50 g/mol
Appearance: White to off-white crystalline powder
Purity: ≥97% (HPLC)
Storage: 2-8°C in inert atmosphere
Hazard Codes: Xi (Irritant)

2. Key Applications & Industry Uses

This boronic ester derivative serves as critical building block in:

  • Suzuki-Miyaura cross-coupling reactions
  • Pharmaceutical intermediates (CNS drugs, kinase inhibitors)
  • Agrochemical research & development
  • Material science applications

3. Operational Best Practices

Handling Protocol:
• Use under nitrogen atmosphere
• Employ dry, aprotic solvents (THF, DMF)
• Optimal reaction temperature: 60-100°C
• Recommended catalyst: Pd(PPh3)4

4. Performance Comparison Table

Parameter Supplier A Supplier B Our Product
Purity 95% 96% ≥97%
Moisture Content 0.5% 0.3% <0.2%
Lead Time 6 weeks 4 weeks 2 weeks

5. Verified Customer Success Stories

Case Study 1: European Pharma Company
• Application: Developed novel dopamine D3 receptor ligands
• Quantity: 15kg batch order
• Result: Achieved 92% coupling efficiency

Case Study 2: Asian Research Institute
• Application: Created fluorescent molecular probes
• Project Duration: 8 months
• Outcome: Published in ACS Applied Materials

6. Technical Support & Purchasing

Contact our chemistry specialists:
✉️ info@vivalr.com
(86) 15866781826

Order Information:
• Minimum Order: 100g
• Custom synthesis available
• GC-MS/HNMR certification included

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