5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine

Product Specifications & Comparative Analysis

Key Parameters

Comparative Analysis with Derivatives

Detailed Applications

Pharmaceutical Intermediates

This compound serves as a critical precursor in synthesizing kinase inhibitors, particularly for oncology therapeutics. Its halogenated structure enables selective binding to ATP pockets in target enzymes.

Agrochemical Research

Used in developing next-generation herbicides due to its stable heterocyclic framework, which enhances metabolic resistance in crop protection formulations.

Operational Guidelines

Storage Protocols

• Store at 2-8°C under inert atmosphere (Ar/N₂)
• Protect from light in amber glass containers

Reaction Optimization

For Suzuki coupling reactions: Use 1.2 eq Pd(PPh₃)₄ catalyst in degassed THF/H₂O (3:1) at 80°C for 12 hours. Typical yields exceed 78%.

Industry Case Studies

Case 1: Oncology Drug Development

A Shanghai-based pharmaceutical company utilized this intermediate in synthesizing third-generation BTK inhibitors, achieving 92% purity after crystallization.

Case 2: Agricultural Formulation

Beijing researchers incorporated derivatives into novel fungicides, demonstrating 98% efficacy against Puccinia striiformis in field trials.

Contact for Technical Consultation

For bulk pricing, SDS documentation, or custom synthesis requirements:

Email: info@vivalr.com
Tel: (86) 15866781826