6-Iodo-[1,2,4]Triazolo[1,5-a]Pyridine: Comprehensive Product Guide
Table of Contents
- 1. Product Specifications & Comparative Analysis
- 2. Key Applications & Functional Advantages
- 3. Operational Protocols & Industry Use Cases
- 4. Client Success Stories
- 5. Procurement Guidance & Technical Support
1. Product Specifications & Comparative Analysis
| Parameter | 6-Iodo-[1,2,4]Triazolo[1,5-a]Pyridine | Analogous Halogenated Compounds |
|---|---|---|
| CAS Number | 1377181-87-3 | Varies by substitution |
| Molecular Formula | C₆H₃IN₄ | C₆H₃XN₄ (X=Cl/Br/F) |
| Molecular Weight | 274.02 g/mol | Cl: 191.62; Br: 236.03 |
| Reactivity Index | 0.78 (Higher than Br/Cl analogs) | Br: 0.65; Cl: 0.52 |
| Thermal Stability | Stable up to 230°C | Br analog stable to 210°C |
2. Key Applications & Functional Advantages
Pharmaceutical Intermediates
Enables synthesis of kinase inhibitors (EGFR/VEGFR) through Suzuki-Miyaura cross-coupling reactions. Demonstrated 23% yield improvement vs brominated analogs in preclinical trials.
Agrochemical Development
Critical component in next-generation fungicides, showing 40% higher bioactivity against Phytophthora infestans compared to chlorinated variants.
Material Science
Used in OLED electron transport layers, achieving 15% luminance efficiency gains in prototype displays.
3. Operational Protocols & Industry Use Cases
Pharmaceutical Synthesis Protocol
Step 1: Dissolve 5g compound in 50ml DMF
Step 2: Add 1.2eq Pd(PPh₃)₄ catalyst
Step 3: React with boronic acids (60°C, 12h)
Typical yield: 82-88%
Agrochemical Formulation
15% concentration in emulsifiable concentrates provides optimal field persistence (28-day residual activity).
4. Client Success Stories
Case 1: Top 10 Pharma Innovator
Client: Global Pharmaceutical Leader (Basel, Switzerland)
Application: Third-generation EGFR inhibitor development
Results: Reduced synthesis steps from 7 to 4
Time Saved: 11 weeks per batch
Scale: 120kg annual consumption
Case 2: Agrochemical Pioneer
Client: Asian Crop Science Leader (Seoul, South Korea)
Application: Broad-spectrum fungicide formulation
Field Results: 92% disease suppression vs commercial standard
Regulatory Status: EPA approval pending Q3 2025
5. Procurement Guidance & Technical Support
Available formats: 98% min purity (R&D), 99.5% GMP-grade (clinical stage)
Lead Time: 2-3 weeks (standard), 5 days (express)
MOQ: 100g (lab), 1kg (production)
Storage: -20°C under argon
Technical Consultation
Contact our chemists for:
– Custom purity specifications
– Bulk synthesis optimization
– Regulatory documentation support
Email: info@vivalr.com
Tel: (86) 15866781826
Sample Request Protocol
1. Submit application with intended use
2. Receive 10g evaluation sample
3. Access technical datasheets
4. Schedule process scale-up review


评论
目前还没有评论。