5-Bromo-2-iodopyridine

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5-Bromo-2-iodopyridine: Comprehensive Product Guide

Table of Contents

Product Overview & Specifications

5-Bromo-2-iodopyridine (CAS 732276-64-7) is a halogenated pyridine derivative with molecular formula C5H3BrIN and molecular weight 299.90 g/mol. Key parameters:

Parameter Value
Purity ≥98% (HPLC)
Appearance White to off-white crystalline powder
Melting Point 112-115°C
Storage 2-8°C in inert atmosphere

Applications & Use Cases

Primary Applications

  • Pharmaceutical intermediates for kinase inhibitors
  • Ligands in cross-coupling reactions (Suzuki, Buchwald-Hartwig)
  • Building block for OLED materials

Industry-Specific Uses

Industry Application
Biotech PROTAC molecule development
Materials Science Conductive polymer synthesis
Agrochemicals Herbicide intermediate

Comparative Analysis

Compound Reactivity Cost Efficiency Stability
5-Bromo-2-iodopyridine High Moderate Excellent
2-Chloro-5-iodopyridine Medium High Good
3-Bromo-2-fluoropyridine Low Low Poor

Industry Case Studies

Case 1: Anticancer Drug Development

A Top 20 Pharma company utilized this compound as a key intermediate in Bruton’s tyrosine kinase (BTK) inhibitor synthesis, achieving 92% yield in Buchwald amination.

Case 2: OLED Material Optimization

Electronics manufacturer reduced production costs by 18% through improved electron-transport layer synthesis using 5-Bromo-2-iodopyridine.

Customer Success Stories

University Research Team

Developed novel Alzheimer’s drug candidates using our compound as a molecular scaffold, published in J. Med. Chem (2024 Impact Factor 6.7).

Contract Manufacturing Organization

Scalved Suzuki-Miyaura coupling to kilogram-scale production with 99.5% purity, meeting FDA ICH Q11 guidelines.

Inquiry & Contact

Request technical documents or pricing:

Contact Method Details
Email info@vivalr.com
Phone (86) 15866781826

Why choose us:

  • ISO 9001-certified production
  • Batch-specific COA provided
  • Custom synthesis available
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