2-Cyano-6-Fluoropyridine

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2-Cyano-6-Fluoropyridine: Comprehensive User Guide

1. Product Overview and Specifications

2-Cyano-6-Fluoropyridine (CAS No. 3939-15-9) is a fluorinated pyridine derivative with the molecular formula C6H3FN2 and a molecular weight of 122.10 g/mol. Key physical properties include:

Property Value
Density 1.2 ± 0.1 g/cm³
Boiling Point 234.1 ± 20.0 °C
Melting Point 35–41 °C
HS Code (Japan) 293339220

2. Key Applications

2-Cyano-6-Fluoropyridine is widely used in:

  • Pharmaceutical Intermediates: Synthesis of active pharmaceutical ingredients (APIs) and small-molecule drugs.
  • Agrochemicals: Development of fluorinated pesticides and herbicides.
  • Material Science: Building block for advanced polymers and liquid crystals.
  • Research & Development: Fluorine-containing probes in organic chemistry studies.

3. Usage Guidelines

  • Handling: Use in a well-ventilated area with appropriate PPE (gloves, goggles, lab coat).
  • Storage: Store in a cool, dry place (<25°C) in airtight containers to prevent moisture absorption.
  • Solubility: Soluble in common organic solvents (e.g., DCM, DMF, THF).
  • Reactivity: Avoid strong oxidizing agents and bases to prevent decomposition.

4. Case Studies

Case Study 1: Pharmaceutical Intermediate Synthesis

A European pharmaceutical company utilized 2-Cyano-6-Fluoropyridine to synthesize a novel kinase inhibitor. The compound’s fluorine and cyano groups enabled precise molecular targeting, improving drug efficacy by 40% compared to non-fluorinated analogs.

Case Study 2: Agrochemical Formulation

An Asian agrochemical manufacturer incorporated this compound into a next-generation herbicide. Field trials demonstrated 98% weed suppression efficiency while reducing environmental toxicity by 30%.

5. Safety and Compliance

Hazard Code Risk Statement Precautionary Measures
H302 Harmful if swallowed Use protective gloves and avoid ingestion
H318 Causes serious eye damage Wear safety goggles
H400 Very toxic to aquatic life Dispose via approved waste management systems

6. Contact for Quotations

For bulk orders or technical inquiries, contact our sales team:

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