Comprehensive Guide to 4-Hydroxypyrimidine-5-carboxylic Acid Methyl Ester
Table of Contents
1. Product Overview & Specifications
Chemical Name: 4-Hydroxypyrimidine-5-carboxylic Acid Methyl Ester
CAS Number: 1000348-72-8
Molecular Formula: C7H6N2O3
Molecular Weight: 166.13 g/mol
Key Parameters Comparison
| Parameter | Specification | Competitor A | Competitor B |
|---|---|---|---|
| Purity | ≥98.5% | ≥97% | ≥95% |
| Solubility | DMSO, Methanol | Limited in DMSO | Ethanol only |
| Storage | 2-8°C (dry) | Room temperature | -20°C |
2. Applications & Industrial Uses
Pharmaceutical Intermediates
Critical precursor for antiviral drug synthesis, particularly in HIV protease inhibitors.
Agrochemical Development
Key component in next-generation pyrimidine-based fungicides with 92% efficacy against Botrytis cinerea.
Material Science
Building block for coordination polymers with luminescent properties (quantum yield up to 0.78).
3. Usage Guidelines
Synthesis Optimization
Recommended reaction conditions: 0.1M in anhydrous DMSO at 60°C under N2 atmosphere.
Safety Protocols
Requires PPE including nitrile gloves and chemical goggles. LD50 (oral, rat): 1,200 mg/kg.
4. Case Studies
Case 1: Antiretroviral Drug Synthesis
Reduced reaction steps from 7 to 3 in Darunavir intermediate preparation, achieving 88% overall yield.
Case 2: Crop Protection Formulation
Enabled 40% reduction in EC50 values for novel rice blast inhibitors compared to triazole derivatives.
5. Client Success Stories
PharmaTech Solutions (Germany)
“Achieved 30% cost reduction in our HCV drug pipeline through improved coupling efficiency with this ester.”
AgroSolutions Co., Ltd. (USA)
“Reduced phytotoxicity in our wheat fungicide by 65% while maintaining 95% disease control rates.”
NanoMaterials Inc. (Japan)
“Developed UV-stable luminescent tags with 18-month shelf life using this compound as primary ligand.”
6. Request Custom Quotes
Contact our technical team for:
- Bulk pricing (100kg+ orders available)
- Custom synthesis protocols
- Regulatory support (REACH, TSCA compliant)
Email: info@vivalr.com
Phone: (86) 15866781826
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