1H-Benzimidazole-2-methanol Cas 4856-97-7

Chemical Name: 1H-Benzimidazole-2-methanol
CAS No.: 4856-97-7
Molecular Fomula: C8H8N2O
Molecular weight:148.16
Appearance: Off-white or light brown powder

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1. Product Overview & Specifications

1H-Benzimidazole-2-methanol (CAS 4856-97-7)

A versatile heterocyclic compound with molecular formula C8H8N2O, molecular weight 148.16 g/mol, appearing as white to off-white crystalline powder.

Parameter Industrial Grade Pharmaceutical Grade
Purity ≥98% ≥99.5%
Melting Point 195-198°C 197-200°C
Residual Solvents <0.5% <0.1%
Storage 2-8°C in airtight container

2. Key Applications

  • Pharmaceutical Intermediate: Critical in synthesizing benzimidazole-derived antiparasitic agents
  • Organic Catalysis: Chelating agent in asymmetric synthesis
  • Material Science: Building block for coordination polymers
  • Research Reagent: Used in kinase inhibition studies

3. Usage Guidelines

Handling Procedures:

  1. Always use PPE (gloves, goggles, lab coat)
  2. Store under nitrogen atmosphere for long-term preservation
  3. Use anhydrous solvents for reactions

Reaction Optimization:

Application Optimal Temp Catalyst Yield
Antifungal Synthesis 60-70°C Pd/C 82-88%
Polymer Formation RT DMAP 75-80%

4. Case Studies

Case 1: Antiparasitic Drug Development

A European pharma company achieved 94% yield in albendazole synthesis using our GMP-grade material, reducing impurity levels by 40% compared to previous suppliers.

Case 2: OLED Material Research

University researchers utilized 1H-Benzimidazole-2-methanol as electron transport layer component, enhancing device efficiency by 22%.

5. Client Testimonials

ABC Pharmaceuticals (India)

“Consistent ≥99.7% purity enabled us to meet FDA validation requirements for new anthelmintic formulations.”

German Materials Corp

“Technical support team provided crucial guidance in scaling up coordination polymer production.”

6. Inquiry & Contact

Request custom synthesis or bulk pricing:

Technical documents available upon request: COA, MSDS, DMF files

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