Boc-D-Pyroglutamic Acid Ethyl Ester (CAS 144978-35-8) Technical Guide
Table of Contents
- Product Specifications & Comparative Analysis
- Functional Applications
- Operational Protocols
- Industry Implementation Cases
- Client Success Stories
- Procurement Consultation
1. Product Specifications & Comparative Analysis
| Parameter | Specification |
|---|---|
| CAS Number | 144978-35-8 |
| Molecular Formula | C13H21NO6 |
| Purity | ≥98% (HPLC) |
| Storage | 2-8°C in sealed container |
| Appearance | White crystalline powder |
| Solubility | Soluble in DMSO, DMF, methanol |
Comparative Analysis
| Feature | Our Product | Standard Grade |
|---|---|---|
| Chiral Purity | >99% ee | 95% ee |
| Thermal Stability | Stable at 25°C | Requires refrigeration |
| Residual Solvents | <0.1% | <0.5% |
2. Functional Applications
This chiral building block demonstrates exceptional utility in:
- Peptide synthesis (N-terminal protection)
- Pharmaceutical intermediates for protease inhibitors
- Conformational studies of cyclic peptides
- Prodrug development for enhanced bioavailability
3. Operational Protocols
Optimal handling parameters:
| Process | Condition |
|---|---|
| Coupling Reactions | DCM, 0-5°C |
| Deprotection | TFA/DCM (1:4 v/v) |
| Purification | Flash chromatography (EtOAc/Hexane) |
4. Industry Implementation Cases
- Antiviral drug development: Key intermediate in NS3/4A protease inhibitor synthesis
- Oncology research: Structural component of HDAC inhibitor candidates
- Neurological studies: Precursor for neuropeptide analogs
5. Client Success Stories
Case 1: Leading European pharma company achieved 23% yield improvement in peptide API synthesis through optimized Boc-D-Pyroglutamic acid ethyl ester utilization.
Case 2: US biotech firm reduced chiral separation costs by 41% using our enantiomerically pure material in kinase inhibitor development.
6. Procurement Consultation
For technical specifications sheets or bulk pricing:
Contact:
Email: info@vivalr.com
Tel: (86) 15866781826
Request quotation with:
- Required quantity
- Shipping destination
- Quality certification needs
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