2-Methyltetrahydrofuran-3-one CAS 3188-00-9

Chemical Name: 2-Methyltetrahydrofuran-3-one
CAS No.: 3188-00-9
Molecular Fomula:C5H8O2
Molecular weight: 100.12
Appearance: Colorless to light yellow liquid

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2-Methyltetrahydrofuran-3-one (CAS 3188-00-9): Comprehensive Guide

Table of Contents

1. Product Overview & Specifications

Parameter Specification Comparison with THF
CAS Number 3188-00-9 N/A
Molecular Formula C5H8O2 Similar to THF (C4H8O)
Boiling Point 140-142°C Higher than THF (66°C)
Flash Point 46°C Safer than THF (-14°C)
Purity ≥99% (GC) Superior to industrial-grade solvents

2. Key Applications & Industry Uses

Pharmaceutical Intermediate Synthesis

Widely used as a green solvent in API production due to its low toxicity and high stability under acidic conditions.

Agrochemical Formulations

Preferred solvent for pyrethroid insecticides requiring controlled evaporation rates.

Flavor & Fragrance Manufacturing

Key component in synthesizing woody/amber fragrance notes with improved shelf-life stability.

3. Real-World Case Studies

Case Study 1: Antibiotic Production Optimization

Client European Pharma Co., Ltd.
Challenge Solvent-induced degradation of β-lactam intermediates
Solution Replaced DCM with 2-MeTHF-3-one in reaction steps
Result Yield increased 18%, reduced purification steps

Case Study 2: Herbicide Stabilization

Client North American AgroChem Inc.
Challenge Phase separation in emulsifiable concentrates
Solution 5% 2-MeTHF-3-one as co-solvent in formulation
Result Storage stability extended from 3 to 18 months

4. Contact for Customized Solutions

Request technical documents or pricing:

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