Chemical Name: 2-Methyltetrahydrofuran-3-one
CAS No.: 3188-00-9
Molecular Fomula:C5H8O2
Molecular weight: 100.12
Appearance: Colorless to light yellow liquid
Parameter | Specification | Comparison with THF |
---|---|---|
CAS Number | 3188-00-9 | N/A |
Molecular Formula | C5H8O2 | Similar to THF (C4H8O) |
Boiling Point | 140-142°C | Higher than THF (66°C) |
Flash Point | 46°C | Safer than THF (-14°C) |
Purity | ≥99% (GC) | Superior to industrial-grade solvents |
Widely used as a green solvent in API production due to its low toxicity and high stability under acidic conditions.
Preferred solvent for pyrethroid insecticides requiring controlled evaporation rates.
Key component in synthesizing woody/amber fragrance notes with improved shelf-life stability.
Client | European Pharma Co., Ltd. |
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Challenge | Solvent-induced degradation of β-lactam intermediates |
Solution | Replaced DCM with 2-MeTHF-3-one in reaction steps |
Result | Yield increased 18%, reduced purification steps |
Client | North American AgroChem Inc. |
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Challenge | Phase separation in emulsifiable concentrates |
Solution | 5% 2-MeTHF-3-one as co-solvent in formulation |
Result | Storage stability extended from 3 to 18 months |
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