4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE CAS 3767-28-0

Chemical Name: 4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE
CAS No.: 3767-28-0
Molecular Fomula: C12H15NO8
Molecular weight: 301.25
Appearance: Powder

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4-Nitrophenyl-alpha-D-glucopyranoside (CAS 3767-28-0) User Guide

Table of Contents

1. Product Overview & Specifications

Parameter Specification
CAS Number 3767-28-0
Molecular Formula C12H15NO8
Purity ≥98% (HPLC)
Appearance White crystalline powder
Solubility Water: 50 mg/mL (clear solution)

2. Key Applications & Use Cases

Primary Applications:

  • Substrate for α-glucosidase enzyme activity assays
  • Diagnostic reagent for carbohydrate metabolism studies
  • Research tool in diabetes drug development

3. Performance Comparison with Alternatives

Feature 4-Nitrophenyl-α-D-glucopyranoside p-Nitrophenyl-β-D-glucopyranoside
Enzyme Specificity α-glucosidase specific β-glucosidase specific
Detection Sensitivity 0.1-10 U/L range 0.5-15 U/L range

4. Industry-Specific Usage Scenarios

Pharmaceutical Research Example:

Used in high-throughput screening of α-glucosidase inhibitors for diabetes treatment. Typical protocol:

  1. Prepare 2 mM substrate solution in phosphate buffer
  2. Incubate with enzyme at 37°C for 30 min
  3. Measure absorbance at 405 nm

5. Customer Success Stories

Case 1: University Research Lab

  • User: Biochemical Research Center, Stanford University
  • Application: Enzyme kinetics study of novel α-glucosidase variants
  • Result: Achieved 90% reaction efficiency with 0.2 mM substrate concentration

Case 2: Pharmaceutical Company

  • User: Novartis AG Drug Discovery Team
  • Application: Screening of herbal extracts for anti-diabetic compounds
  • Result: Identified 3 potential inhibitors with IC50 < 50 μM

6. Technical Support & Inquiry

For bulk orders or technical specifications:

Request free sample or MSDS: [Submit inquiry form]

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