3,5-Dichlorobenzoic Acid (CAS 51-36-5): Comprehensive User Guide

1. Product Overview & Specifications

Basic Properties

Parameter Value
Chemical Name 3,5-Dichlorobenzoic Acid
CAS Number 51-36-5
Molecular Formula C7H4Cl2O2
Molecular Weight 191.01 g/mol
Appearance White crystalline powder
Melting Point 188-192°C
Solubility Soluble in organic solvents (ethanol, DMSO), slightly soluble in water

Comparative Analysis

Feature 3,5-Dichlorobenzoic Acid 2,4-Dichlorobenzoic Acid 3,4-Dichlorobenzoic Acid
CAS Number 51-36-5 50-84-0 5664-02-6
Thermal Stability High Moderate Low
Reactivity Superior electrophilic substitution Moderate Limited

2. Key Applications & Use Cases

Pharmaceutical Intermediates

Used in synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and antifungal agents.

Agrochemical Production

Critical precursor for herbicides and fungicides due to chlorine substituent stability.

Organic Synthesis

Enables preparation of esters, amides, and coordination complexes via carboxyl group reactivity.

3. Industry-Specific Case Studies

Case 1: Antimicrobial Drug Development

European pharma company achieved 92% yield in synthesizing novel quinolone antibiotics using 3,5-DCBA as key intermediate.

Case 2: Herbicide Formulation

US agrochemical manufacturer reduced synthesis steps from 7 to 4 using 51-36-5 as nucleophilic agent.

4. Customer Success Stories

ABC Pharmaceuticals (Germany)

“Adoption of 3,5-DCBA increased API production efficiency by 35% while meeting EP 10.0 purity standards.”

GreenChem Agrosolutions (USA)

“Achieved 20% cost reduction in pre-emergence herbicide production through optimized 51-36-5 integration.”

5. Request a Quote

Contact our technical team for bulk pricing, COA, and custom synthesis options:

✓ ISO 9001 Certified ✓ Batch-to-Batch Consistency ✓ Technical Support

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