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3,5-Dichlorobenzoic Acid (CAS 51-36-5): Comprehensive User Guide

Table of Contents

1. Product Overview & Specifications

Basic Properties

Parameter Value
Chemical Name 3,5-Dichlorobenzoic Acid
CAS Number 51-36-5
Molecular Formula C7H4Cl2O2
Molecular Weight 191.01 g/mol
Appearance White crystalline powder
Melting Point 188-192°C
Solubility Soluble in organic solvents (ethanol, DMSO), slightly soluble in water

Comparative Analysis

Feature 3,5-Dichlorobenzoic Acid 2,4-Dichlorobenzoic Acid 3,4-Dichlorobenzoic Acid
CAS Number 51-36-5 50-84-0 5664-02-6
Thermal Stability High Moderate Low
Reactivity Superior electrophilic substitution Moderate Limited

2. Key Applications & Use Cases

Pharmaceutical Intermediates

Used in synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and antifungal agents.

Agrochemical Production

Critical precursor for herbicides and fungicides due to chlorine substituent stability.

Organic Synthesis

Enables preparation of esters, amides, and coordination complexes via carboxyl group reactivity.

3. Industry-Specific Case Studies

Case 1: Antimicrobial Drug Development

European pharma company achieved 92% yield in synthesizing novel quinolone antibiotics using 3,5-DCBA as key intermediate.

Case 2: Herbicide Formulation

US agrochemical manufacturer reduced synthesis steps from 7 to 4 using 51-36-5 as nucleophilic agent.

4. Customer Success Stories

ABC Pharmaceuticals (Germany)

"Adoption of 3,5-DCBA increased API production efficiency by 35% while meeting EP 10.0 purity standards."

GreenChem Agrosolutions (USA)

"Achieved 20% cost reduction in pre-emergence herbicide production through optimized 51-36-5 integration."

5. Request a Quote

Contact our technical team for bulk pricing, COA, and custom synthesis options:

✓ ISO 9001 Certified ✓ Batch-to-Batch Consistency ✓ Technical Support

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Drug impurities to intermediates. Years of expertise.

Experience in the synthesis of complex compounds derived from American technology
Focus on the synthesis of difficult compounds
ISO 17034 dual system certification
National high-tech enterprise
5000+ square meters R&D center
A 70+ R&D team led by Chinese and foreign doctors
150 pieces (sets) of R&D equipment, 120+ fume hoods
18 patents

Solid QMS. Offer top-quality products and services.

Through more than ten years of continuous technological innovation and experience accumulation, the team's R&D personnel have established a complete quality management system for CATO, and have successively obtained ISO9001, ISO17034, CNAS and other international certifications.
It has successfully passed on-site inspections from the United States, Australia, Poland, Japan and domestic pharmaceutical company customers and institutions many times, providing high-quality one-stop services for R&D and production of new drugs around the world.

More than 150 sets of equipment to ensure quality.

The emphasis on quality is the basis for our survival and development, and is the most basic requirement for the products and services we provide. CATO has established a scientific, strict and comprehensive quality prevention and assurance system in accordance with international quality standards. Through advanced testing equipment such as GC-MS, chromatograph, nuclear magnetic resonance, scanning electron microscope, and ultraviolet light, quality management is implemented into every aspect of production and operation activities such as raw materials, inventory, production, testing, sales, verification, and training, and "All actions are controlled and traceable" as the work code of conduct for CATO employees.

Over 1000 cases. Synthesize complex compounds.

Currently, CATO serves more than 500 pharmaceutical companies, biotechnology and other companies around the world. Project types cover the entire cycle from pre-clinical to commercialization stages. As of 2020, CATO has delivered more than 1,000 projects in total.
The company has core technologies in key core technology fields such as high-end fluorine chemistry, asymmetric chiral synthesis, glycoside and biological enzyme technology, and continuous microreactors.

About the company

International Standard Chemicals Sell To All Over The World

FAQ

Does it support auditing?

Support, please make an appointment one day in advance. Company address: Room 716, Building 3, Ligao International Garden, No.1222 West Aoti Road, Lixia District, Jinan City, Shandong Province, P.R. China

Whether to provide samples?

Free samples can be provided for low value products, and small packaging specifications can be purchased for high value products.

Delivery time

Under normal circumstances, all items are in stock and will be shipped before 4 o'clock on the same day. Some products are produced to order, depending on the workshop situation and production schedule.

What is the production capacity?

At present, the company's workshop production equipment is mainly based on laboratories and pilot lines, with a maximum daily production capacity of 1.5 tons.

Can additional test indicators be added?

We can provide moisture, UV, IR, HNMR, CNMR, two-dimensional nuclear magnetic spectroscopy, optical rotation detection, elemental analysis, TGA analysis and residue analysis and other related tests to support personalized needs.

Technical direction

In the early stage, our company mainly engaged in drug impurity synthesis and standard product production, with core technologies in chirality, fluorine chemistry, and heterocycles.

Why Chem-iso’s delivery rate is guaranteed to be 99.99%

5000+

square meter R&D center

150+

China(set) of R&D equipment

150+

Fume hood

180+

R&D team

User’evaluation of us

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