Tonalide Cas 21145-77-7

Chemical Name: Tonalide
Other Name: Tonalid; 6-Acetyl-1,1,2,4,4,7-hexamethyltetralin
CAS No.: 21145-77-7
Molecular Fomula: C18H26O

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Comprehensive Guide to Tonalide (CAS 21145-77-7)

1. Product Overview & Specifications

Tonalide (CAS 21145-77-7), also known as 7-acetyl-1,1,3,4,4,6-hexamethyltetralin, is a premium synthetic musk widely used in fragrances. Key specifications include:

Parameter Value
Molecular Formula C18H26O
Molecular Weight 258.4 g/mol
Appearance White crystalline solid
Melting Point 55–56°C
Key Advantage Superior light stability and cost-effectiveness compared to nitro and macrocyclic musks

2. Key Applications

Tonalide is a versatile ingredient in:

  • Perfumes & Cosmetics: Enhances longevity and warmth in floral and oriental fragrances.
  • Personal Care Products: Stabilizes scents in soaps, lotions, and bath oils.
  • Household Cleaners: Provides persistent freshness in detergents and fabric softeners.
  • Biomarker Research: Used in environmental and toxicological studies due to its traceability.

3. Usage Guidelines

Optimal Incorporation:

  • Recommended dosage: 0.1–2.0% in fragrance formulations.
  • Compatible with ethanol, essential oils, and glycol-based carriers.
  • Stable under UV exposure and pH ranges of 4–9.

Safety Notes: While Tonalide exhibits low acute toxicity, prolonged environmental accumulation requires adherence to regional regulatory limits.

4. Industry Case Studies

Case 1: Luxury Perfume Brand

  • Challenge: Reformulate a flagship perfume to comply with EU allergen restrictions.
  • Solution: Replaced nitro musks with Tonalide for enhanced stability and regulatory compliance.
  • Result: 20% increase in shelf life and 15% higher consumer satisfaction.

Case 2: Eco-Friendly Detergent

  • Challenge: Develop a biodegradable detergent with lasting fragrance.
  • Solution: Integrated Tonalide at 0.5% concentration with plant-derived surfactants.
  • Result: Achieved 8-hour fragrance retention while meeting OECD biodegradability standards.

5. Client Success Stories

Client A: Global Cosmetics Manufacturer

  • Used Tonalide in a bestselling body lotion series to replace animal-derived musks.
  • Outcome: 30% reduction in production costs and vegan certification within 6 months.

Client B: Niche Fragrance Studio

  • Leveraged Tonalide’s thermal stability in candle fragrance development.
  • Outcome: Consistent scent diffusion at high temperatures, leading to a 40% sales increase.

6. Contact for Inquiries

For technical specifications, bulk pricing, or formulation support:

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