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Specialized inTonalide Cas 21145-77-7and related product development and production

Chemical Name: Tonalide
Other Name: Tonalid; 6-Acetyl-1,1,2,4,4,7-hexamethyltetralin
CAS No.: 21145-77-7
Molecular Fomula: C18H26O

Samples: Available / Stock: Sufficient
Estimated delivery time: 3-5 days

Comprehensive Guide to Tonalide (CAS 21145-77-7)

Table of Contents

1. Product Overview & Specifications

Tonalide (CAS 21145-77-7), also known as 7-acetyl-1,1,3,4,4,6-hexamethyltetralin, is a premium synthetic musk widely used in fragrances. Key specifications include:

Parameter Value
Molecular Formula C18H26O
Molecular Weight 258.4 g/mol
Appearance White crystalline solid
Melting Point 55–56°C
Key Advantage Superior light stability and cost-effectiveness compared to nitro and macrocyclic musks

2. Key Applications

Tonalide is a versatile ingredient in:

  • Perfumes & Cosmetics: Enhances longevity and warmth in floral and oriental fragrances.
  • Personal Care Products: Stabilizes scents in soaps, lotions, and bath oils.
  • Household Cleaners: Provides persistent freshness in detergents and fabric softeners.
  • Biomarker Research: Used in environmental and toxicological studies due to its traceability.

3. Usage Guidelines

Optimal Incorporation:

  • Recommended dosage: 0.1–2.0% in fragrance formulations.
  • Compatible with ethanol, essential oils, and glycol-based carriers.
  • Stable under UV exposure and pH ranges of 4–9.

Safety Notes: While Tonalide exhibits low acute toxicity, prolonged environmental accumulation requires adherence to regional regulatory limits.

4. Industry Case Studies

Case 1: Luxury Perfume Brand

  • Challenge: Reformulate a flagship perfume to comply with EU allergen restrictions.
  • Solution: Replaced nitro musks with Tonalide for enhanced stability and regulatory compliance.
  • Result: 20% increase in shelf life and 15% higher consumer satisfaction.

Case 2: Eco-Friendly Detergent

  • Challenge: Develop a biodegradable detergent with lasting fragrance.
  • Solution: Integrated Tonalide at 0.5% concentration with plant-derived surfactants.
  • Result: Achieved 8-hour fragrance retention while meeting OECD biodegradability standards.

5. Client Success Stories

Client A: Global Cosmetics Manufacturer

  • Used Tonalide in a bestselling body lotion series to replace animal-derived musks.
  • Outcome: 30% reduction in production costs and vegan certification within 6 months.

Client B: Niche Fragrance Studio

  • Leveraged Tonalide’s thermal stability in candle fragrance development.
  • Outcome: Consistent scent diffusion at high temperatures, leading to a 40% sales increase.

6. Contact for Inquiries

For technical specifications, bulk pricing, or formulation support:

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Drug impurities to intermediates. Years of expertise.

Experience in the synthesis of complex compounds derived from American technology
Focus on the synthesis of difficult compounds
ISO 17034 dual system certification
National high-tech enterprise
5000+ square meters R&D center
A 70+ R&D team led by Chinese and foreign doctors
150 pieces (sets) of R&D equipment, 120+ fume hoods
18 patents

Solid QMS. Offer top-quality products and services.

Through more than ten years of continuous technological innovation and experience accumulation, the team's R&D personnel have established a complete quality management system for CATO, and have successively obtained ISO9001, ISO17034, CNAS and other international certifications.
It has successfully passed on-site inspections from the United States, Australia, Poland, Japan and domestic pharmaceutical company customers and institutions many times, providing high-quality one-stop services for R&D and production of new drugs around the world.

More than 150 sets of equipment to ensure quality.

The emphasis on quality is the basis for our survival and development, and is the most basic requirement for the products and services we provide. CATO has established a scientific, strict and comprehensive quality prevention and assurance system in accordance with international quality standards. Through advanced testing equipment such as GC-MS, chromatograph, nuclear magnetic resonance, scanning electron microscope, and ultraviolet light, quality management is implemented into every aspect of production and operation activities such as raw materials, inventory, production, testing, sales, verification, and training, and "All actions are controlled and traceable" as the work code of conduct for CATO employees.

Over 1000 cases. Synthesize complex compounds.

Currently, CATO serves more than 500 pharmaceutical companies, biotechnology and other companies around the world. Project types cover the entire cycle from pre-clinical to commercialization stages. As of 2020, CATO has delivered more than 1,000 projects in total.
The company has core technologies in key core technology fields such as high-end fluorine chemistry, asymmetric chiral synthesis, glycoside and biological enzyme technology, and continuous microreactors.

About the company

International Standard Chemicals Sell To All Over The World

FAQ

Does it support auditing?

Support, please make an appointment one day in advance. Company address: Room 716, Building 3, Ligao International Garden, No.1222 West Aoti Road, Lixia District, Jinan City, Shandong Province, P.R. China

Whether to provide samples?

Free samples can be provided for low value products, and small packaging specifications can be purchased for high value products.

Delivery time

Under normal circumstances, all items are in stock and will be shipped before 4 o'clock on the same day. Some products are produced to order, depending on the workshop situation and production schedule.

What is the production capacity?

At present, the company's workshop production equipment is mainly based on laboratories and pilot lines, with a maximum daily production capacity of 1.5 tons.

Can additional test indicators be added?

We can provide moisture, UV, IR, HNMR, CNMR, two-dimensional nuclear magnetic spectroscopy, optical rotation detection, elemental analysis, TGA analysis and residue analysis and other related tests to support personalized needs.

Technical direction

In the early stage, our company mainly engaged in drug impurity synthesis and standard product production, with core technologies in chirality, fluorine chemistry, and heterocycles.

Why Chem-iso’s delivery rate is guaranteed to be 99.99%

5000+

square meter R&D center

150+

China(set) of R&D equipment

150+

Fume hood

180+

R&D team

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