Sodium tert-butoxide CAS 865-48-5

Chemical Name: Sodium tert-butoxide
Synonyms: Sodium 2-methylpropan-2-olate; NatB
CAS No.: 865-48-5
Molecular Fomula: C4H9NaO
Molecular weight: 96.1
Appearance: White crystal
Assay: ≥99.0%

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Table of Contents

Sodium tert-butoxide (CAS 865-48-5) Technical Specifications

Chemical Profile

Parameter Specification
CAS Number 865-48-5
Molecular Formula C4H9NaO
Appearance White to off-white powder
Purity Grade Industrial (≥97%), Pharmaceutical (≥99%)
Storage Conditions 2-8°C in inert atmosphere

Comparative Analysis

Property Sodium tert-butoxide Potassium tert-butoxide
Basicity (pKa) 17.5 19.0
Solubility in THF 450 g/L 320 g/L
Reaction Efficiency High Exceptional

Industrial Applications of Sodium tert-butoxide

Pharmaceutical Synthesis

Essential in β-lactam antibiotic production and steroid derivatization processes.

Polymer Chemistry

Catalyzes living anionic polymerization for specialty elastomers (35-60% yield improvement).

Operational Protocols

Material Handling

Requires dry nitrogen environment with humidity <15 ppm during processing.

Documented Implementation Cases

Antiviral Drug Intermediate Synthesis

Enabled 92% yield in oseltamivir phosphate precursor reactions.

Client Implementation Results

Specialty Chemical Manufacturer (Hunan, China)

Achieved 40% reduction in reaction time for organotin compounds production.

Technical Partnership Inquiry

Contact our engineering team for batch-specific specifications:

Email: info@vivalr.com
Tel: (86) 15866781826

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