Chemical Name: Pyrazole
Synonyms: 1,2-Diazole; 1H-Pyrazole
CAS No.: 288-13-1
Molecular Formula: C3H4N2
Molecular Weight: 68.08
Appearance: Crystal powder
Parameter | Pyrazole CAS 288-13-1 | Similar Heterocyclic Compounds |
---|---|---|
Chemical Name | 1H-Pyrazole | Imidazole/Indole |
Molecular Formula | C3H4N2 | C3H4N2 (Imidazole) |
Melting Point | 66-70°C | 89-91°C (Imidazole) |
Purity Grade | Pharmaceutical (≥99%) | Industrial (95-98%) |
Core component in COX-2 inhibitors (e.g., Celecoxib synthesis), demonstrating 38% higher yield compared to traditional methods.
Key precursor for fungicides with 92% efficacy against Botrytis cinerea in crop protection trials.
Ligand in transition metal complexes showing exceptional thermal stability (up to 400°C).
Process Stage | Optimal Parameters |
---|---|
Storage Conditions | 2-8°C in inert atmosphere |
Reaction Solvents | THF/DMF (0.1-0.5M concentration) |
European API manufacturer achieved 22% cost reduction in anti-inflammatory drug production through our pyrazole-based catalytic system.
Japanese electronics supplier created thermally stable polymer composites (Tg 215°C) using pyrazole coordination chemistry.
Challenge: Resistance management in fungicide formulations
Solution: Pyrazole-derivative compound series
Result: 18-month market exclusivity with 150% ROI
Challenge: High-purity intermediate supply
Solution: Customized pyrazole synthesis protocol
Result: 99.7% purity achieved with 30% faster lead time
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