Table of Contents
Sodium Hydroxymethylglycinate (CAS 70161-44-3): Key Specifications
| Parameter | Value |
|---|---|
| CAS Number | 70161-44-3 |
| Molecular Formula | C₃H₆NNaO₃ |
| Appearance | Colorless to pale yellow liquid |
| pH Range | 3.0-8.0 |
| Solubility | Water-soluble (≥50%) |
| Preservative Efficacy | Broad-spectrum against bacteria, yeast, mold |
Comparative Analysis with Alternative Preservatives
| Preservative | pH Stability | Cosmetic Sensitization Risk | MIC against E. coli |
|---|---|---|---|
| Sodium Hydroxymethylglycinate | 3-8 | Low | 0.1% |
| Phenoxyethanol | 3-10 | Moderate | 0.5% |
| Potassium Sorbate | 2-6.5 | Low | 0.3% |
Industrial & Cosmetic Applications
Primary Functional Uses
- Personal Care: Shampoos, conditioners (0.1-0.5% concentration)
- Cosmetic Formulations: pH-sensitive emulsions & serums
- Industrial Fluids: Metalworking compounds, adhesives
Technical Advantages
- Formaldehyde-free preservation mechanism
- Compatible with cationic surfactants
- Stable at high-temperature processing (up to 80°C)
Performance Benchmarking Data
| Test Parameter | Result | ASTM Method |
|---|---|---|
| 28-day Microbial Challenge | Pass (USP 51) | D2574 |
| Corrosion Inhibition | 85% efficiency | G31 |
Formulation Recommendations
Optimal Usage Parameters
- Add at 40-50°C during cooling phase
- Combine with chelating agents (EDTA) for hard water stability
- Max concentration: 1.0% in leave-on products
Documented Industry Implementations
Case Study 1: Natural Skincare Brand (Spain)
- Challenge: Reformulate organic face cream to meet EU 1223/2009
- Solution: 0.3% Sodium Hydroxymethylglycinate + 0.2% Gluconolactone
- Result: 24-month shelf life with 99.9% microbial reduction
Case Study 2: Industrial Lubricant Manufacturer (Germany)
- Challenge: Prevent bacterial growth in water-based cutting fluids
- Solution: 0.8% preservative in pH 8.5 system
- Result: 12-month stability without pH drift
Technical Consultation & Ordering
For formulation assistance or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826
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