5-Chloro-1,3-dimethoxybenzene CAS 7051-16-3

Chemical Name: 5-Chloro-1,3-dimethoxybenzene
CAS No.: 7051-16-3
Appearance: White to yellow or pink crystalline powder
Assay:≥97.0%

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5-Chloro-1,3-dimethoxybenzene (CAS 7051-16-3) Comprehensive Guide

Table of Contents

1. Product Overview & Specifications

Chemical Name: 1-Chloro-3,5-dimethoxybenzene

CAS: 7051-16-3

Molecular Formula: C8H9ClO2

Molecular Weight: 172.61 g/mol

Purity: ≥97.0% (GC)

Physical Form: White to off-white crystalline powder

Storage: 2-8°C in airtight container

2. Key Applications & Industry Uses

This aromatic ether compound serves as:

  • Critical intermediate in pharmaceutical synthesis (e.g., antipsychotic APIs)
  • Precursor for advanced material science applications
  • Building block for agrochemical research
  • Cross-coupling reactions in organic chemistry

3. Performance Comparison with Analogues

Parameter 5-Chloro-1,3-dimethoxybenzene 2-Chloro-1,3-dimethoxybenzene 5-Bromo-2-chloro analogue
CAS Number 7051-16-3 7051-15-2 427886-20-2
Molecular Weight 172.61 172.61 251.5
Reactivity Moderate electrophilic substitution Higher ortho-directing effect Enhanced halogen exchange potential

4. Operational Best Practices

Handling Protocols:

  • Use NIOSH-approved respirator during bulk processing
  • Conduct reactions under inert atmosphere
  • Optimize solvent selection (DCM/THF recommended)

5. Verified Client Success Stories

Case 1: Pharmaceutical Innovator (Shanghai)

  • Application: Synthesis of dopamine D2 receptor antagonists
  • Outcome: 22% yield improvement vs traditional routes
  • Scale: 150kg/month production

Case 2: Electronic Materials Manufacturer (Shenzhen)

  • Application: Liquid crystal precursor development
  • Result: Achieved 99.3% HPLC purity
  • Volume: 50kg pilot batch success

6. Technical Support & Procurement

Our chemical engineering team provides:

  • Custom synthesis optimization
  • Regulatory compliance documentation
  • Just-in-time delivery solutions

Contact Technical Specialists:
Email: info@vivalr.com
Tel: (86) 15866781826

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