1 4-Dibromobutane Cas 110-52-1

Table of Contents

• 1. Product Overview & Specifications
• 2. Key Applications & Industrial Uses
• 3. Operational Guidelines & Best Practices
• 4. Documented Use Cases
• 5. Verified Client Implementations
• 6. Request Customized Solution

1. Product Overview & Specifications

1,4-Dibromobutane Technical Parameters (CAS 110-52-1)

Material Safety Data

• UN Number: 2929
• Hazard Class: 6.1
• Flash Point: 93°C

2. Key Applications & Industrial Uses

Pharmaceutical Intermediate Synthesis

Critical component in production of antihistamine APIs through nucleophilic substitution reactions. Enables precise molecular architecture in:

• Anticancer drug precursors
• Neurological disorder medications
• Antiviral compound synthesis

Polymer Modification

Essential cross-linking agent for engineering plastics and specialty rubbers:

• Increases thermal stability in polyamide composites
• Enhances chemical resistance in fluoropolymers
• Improves mechanical strength in epoxy formulations

3. Operational Guidelines & Best Practices

Reaction Optimization

Safety Protocols

• Mandatory PPE: Chemical goggles + Butyl rubber gloves
• Ventilation Requirements: ≥10 air changes/hour
• Spill Management: Neutralize with sodium carbonate

4. Documented Use Cases

High-Yield Pharmaceutical Synthesis

Optimized coupling reaction achieving 92% yield in crizotinib intermediate production through controlled stoichiometric ratios.

Advanced Material Development

Enabled 35% improvement in polyether ether ketone (PEEK) heat deflection temperature through strategic cross-linking.

5. Verified Client Implementations

Case 1: Multinational Pharma Corporation

• Application: Large-scale production of tyrosine kinase inhibitors
• Volume: 8 metric tons/year
• Result: Reduced impurity profile by 40% vs previous supplier

Case 2: Specialty Chemical Manufacturer

• Application: Flame-retardant additive synthesis
• Technical Achievement: Achieved UL94 V-0 rating in PC/ABS blends
• Economic Benefit: 18% reduction in production costs

6. Request Customized Solution

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• Custom purity specifications
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