Escin (CAS 6805-41-0): Comprehensive Product Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | Escin (CAS 6805-41-0) |
|---|---|
| Chemical Name | Escin (Aescine) |
| CAS Number | 6805-41-0 |
| Molecular Formula | C55H86O24 |
| Molecular Weight | 1131.26 g/mol |
| Purity | ≥97% (HPLC, mixture of isomers) |
Supplier Comparison
| Supplier | Purity | Packaging | Price Range |
|---|---|---|---|
| MedChemExpress | ≥98% | 10 mg – 25 g | Contact for Quote |
| Yuanye Bio-Tech | 97% | 1 g – 25 g | $400 – $4,000 |
| Wuhan Huajiu Pharma | N/A | Bulk orders | Negotiable |
2. Key Applications & Mechanisms
Therapeutic Applications
- Vascular Protection: Enhances venous tone and reduces capillary permeability
- Anti-inflammatory: Inhibits prostaglandin E2 and histamine release
- Anti-edema: Reduces post-traumatic/swelling through proteinase inhibition
- Analgesic: Modulates nociceptive pathways in chronic pain management
Research Applications
- Apoptosis studies in cancer research
- Venous insufficiency models in preclinical trials
- Natural product derivatization for drug discovery
3. Recommended Usage Protocols
In Vitro Testing
- Solubility: Dissolve in DMSO (10 mM stock)
- Working Concentration: 1-100 μM depending on cell type
- Incubation Time: 24-72 hours for apoptosis assays
4. Verified Case Studies
Case 1: Pharmaceutical R&D (EU)
- Application: Development of topical anti-inflammatory cream
- Result: 40% reduction in edema vs. placebo in Phase II trials
Case 2: Nutraceutical Manufacturer (USA)
- Application: Venous circulation support capsules
- Result: Marketed product with 300 mg Escin/dose, GRAS status
5. Inquiry & Custom Solutions
For technical specifications, bulk pricing, or custom synthesis requirements:
| info@vivalr.com | |
| Phone | (86) 15866781826 |
| Lead Time | 2-4 weeks for GMP-grade production |
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