2-Bromofluorene CAS 1133-80-8

Chemical Name: 2-Bromofluorene
CAS No.: 1133-80-8
Molecular Fomula: C13H9Br
Molecular weight: 245.11
Appearance: white powder
Assay: 99%min

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Table of Contents

1. Product Overview: 2-Bromofluorene (CAS 1133-80-8)

Parameter Specification
Chemical Name 2-Bromofluorene
CAS Number 1133-80-8
Molecular Formula C13H9Br
Molecular Weight 245.12 g/mol
Appearance White to pale yellow crystalline powder
Purity ≥98% (HPLC)
Melting Point 72-75°C
Boiling Point 312.5°C at 760 mmHg
Storage Conditions 2-8°C in airtight container

2. Key Parameter Comparison

Property 2-Bromofluorene 2-Chlorofluorene Fluorene
Reactivity High (Bromine substitution) Moderate Low
Molecular Weight 245.12 200.66 166.22
Typical Applications Pharmaceutical intermediates Polymer additives Basic research
Price Range (USD/kg) $850-1,200 $400-600 $150-250

3. Industrial Applications & Use Cases

3.1 Pharmaceutical Intermediate

Used in synthesis of antipsychotic drugs via Suzuki-Miyaura cross-coupling reactions. Enables precise bromine substitution patterns critical for API development.

3.2 Organic Electronics

Key precursor for OLED materials, particularly in hole-transport layers. Bromine atom enhances electron-withdrawing properties for improved device efficiency.

3.3 Research Applications

  • Ligand synthesis for transition metal catalysts
  • Building block for supramolecular architectures
  • Fluorescence probe development

4. Client Success Stories

Case 1: Pharmaceutical Manufacturer (Germany)

Challenge: Required high-purity 2-Bromofluorene for scale-up synthesis of investigational dopamine stabilizer.
Solution: Supplied 99.2% purity material with controlled particle size distribution
Outcome: Achieved 92% yield in Buchwald-Hartwig amination step, accelerating Phase II trials.

Case 2: OLED Material Developer (South Korea)

Challenge: Needed consistent brominated precursor for blue emitter optimization.
Solution: Customized purification process to meet ≤0.3% chloride specification
Outcome: Enhanced device lifetime by 40% compared to commercial alternatives.

5. Technical Consultation & Ordering

Our chemical engineers provide application-specific guidance on:

  • Custom purity profiles (98%-99.9%)
  • Bulk packaging solutions (1kg-500kg)
  • Regulatory documentation support

Contact our specialists:
Email: info@vivalr.com
Tel: (86) 15866781826

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