Esomeprazole (CAS 119141-88-7) Technical Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | Esomeprazole | Omeprazole (Reference) |
|---|---|---|
| CAS Number | 119141-88-7 | 73590-58-6 |
| Molecular Formula | C17H19N3O3S | C17H19N3O3S |
| Molecular Weight | 345.42 g/mol | 345.42 g/mol |
| Optical Rotation [α]D20 | -155° (c=0.5 in CHCl3) | Racemic mixture |
| Proton Pump Inhibition | >98% enantiomeric purity | 50% active enantiomer |
2. Clinical & Industrial Applications
Therapeutic Uses
- First-line treatment for erosive esophagitis (Grade C/D)
- Zollinger-Ellison syndrome management
- Adjuvant therapy with antibiotics for H. pylori eradication
Research Applications
- Legumain protease inhibition studies in oncology research
- Pharmaceutical reference standard for HPLC analysis
- Metabolic pathway studies using isotopically labeled variants
3. Supplier Case Studies
Case 1: TargetMol (Shanghai TaoShu Biotech)
- Application: Supplied 98.2% purity material for metastatic cancer research
- Specifications: 25mg-100mg analytical standards
- Technical Support: Provided NMR/HPLC validation data
Case 2: Hubei Wonder Chemistry
- Application: Bulk API production for generic formulations
- Scale: >100kg batches with ISO 9001 certification
- Logistics: Established cold chain distribution to EU markets
Case 3: Shenzhen Healthshine Biotech
- Application: IVD reagent development
- Customization: Developed 5mg/mL PBS buffer formulation
- Compliance: Met USP-NF monograph requirements
4. Inquiry Guidance
For technical specifications sheets, MSDS documentation, or customized synthesis requirements:
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