1. Product Overview & Specifications

Tetraethyl Orthocarbonate (CAS 78-09-1)

Molecular Formula: C₉H₂₀O₄
Molecular Weight: 192.25 g/mol
Appearance: Colorless to pale yellow liquid
Boiling Point: 210-212°C
Density: 1.02 g/cm³ at 20°C
Solubility: Miscible with organic solvents (ethanol, ether)

Comparative Analysis

2. Key Applications & Use Cases

Core Applications:

• Organic Synthesis: As protecting group for carbonyl compounds
• Polymer Chemistry: Crosslinking agent for silicone resins
• Pharmaceuticals: Intermediate in antiviral drug synthesis
• Materials Science: Precursor for ceramic coatings

Performance Advantages:

• Superior thermal stability (up to 250°C)
• Low viscosity for easy handling
• High purity (≥99.5%) for sensitive reactions

3. Step-by-Step Usage Guidelines

Typical Reaction Protocol:

1. Prepare anhydrous reaction environment (N₂ atmosphere)
2. Mix with substrate alcohol in 1:4 molar ratio
3. Add catalytic HCl (0.5-1.0 mol%)
4. Reflux at 80°C for 6-8 hours
5. Neutralize with NaHCO₃ solution

Safety Precautions:

• Use chemical-resistant gloves (nitrile recommended)
• Store in amber glass at 2-8°C
• Avoid contact with strong oxidizers

4. Real-World Customer Case Studies

Case Study 1: ChemSynth Ltd. (Germany)

Challenge: Required high-purity protecting agent for Taxol intermediate synthesis
Solution: Implemented CAS 78-09-1 with 99.7% purity
Result: Increased reaction yield from 68% to 82%

Case Study 2: NanoMaterials Inc. (USA)

Challenge: Developing heat-resistant silicone coatings
Solution: Used as crosslinker at 15% w/w concentration
Result: Achieved 300°C thermal stability in final product

Case Study 3: PharmaTech Solutions (India)

Challenge: Scaling up Remdesivir analog production
Solution: Optimized reaction conditions with CAS 78-09-1
Result: Reduced side products by 40% vs. traditional methods

5. Technical Support & Inquiry

For technical specifications sheets or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826

Why Choose Our Product?

• ISO 9001-certified production
• Customizable packaging (1kg to 1000kg drums)
• 24/7 technical support