6-Carboxytetramethylrhodamine (CAS 91809-67-5) User Guide
Table of Contents
- Product Overview & Specifications
- Applications & Use Cases
- Performance Comparison
- Industry Case Studies
- Inquiry & Ordering
Product Overview & Specifications
6-Carboxytetramethylrhodamine (6-TAMRA) (CAS 91809-67-5) is a red-emitting fluorescent dye with carboxylic acid functionality, widely used in biomolecular labeling. Key parameters:
| Parameter | Value |
|---|---|
| Molecular Weight | 443.45 g/mol |
| Excitation/Emission | 555 nm/580 nm |
| Purity | >98% (HPLC) |
| Solubility | DMSO, Water (pH>7) |
Comparative Analysis
| Dye | Quantum Yield | Photostability | Conjugation Efficiency |
|---|---|---|---|
| 6-TAMRA | 0.68 | High | 90-95% |
| FITC | 0.79 | Medium | 80-85% |
Applications & Use Cases
Primary Applications
- Nucleic acid labeling for FISH assays
- Protein conjugation in flow cytometry
- Microscopy-based cellular tracking
Protocol Example: Oligonucleotide Labeling
- Activate 6-TAMRA with EDC/NHS chemistry
- Mix with amine-modified oligonucleotides (1:3 molar ratio)
- Purify via HPLC (C18 column)
Industry Case Studies
Case 1: Cancer Biomarker Research (Genomics Lab Inc.)
Used 6-TAMRA-labeled probes for CTC detection in liquid biopsies, achieving 94% detection specificity in pancreatic cancer models.
Case 2: Neuroimaging Study (NeuroVision LLC)
Implemented 6-TAMRA-conjugated antibodies for real-time synaptic activity monitoring, enabling 5ms temporal resolution in live tissue imaging.
Inquiry & Ordering
Request technical specifications or bulk quotes:
- Email: info@vivalr.com
- Tel: (86) 15866781826
Include your application requirements and preferred shipment terms for optimized service.
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