Glycyrrhizic Acid Trisodium Salt Hydrate (CAS 71277-78-6): Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | Glycyrrhizic Acid Trisodium Salt Hydrate | Competitor A | Competitor B |
|---|---|---|---|
| CAS Number | 71277-78-6 | N/A | N/A |
| Purity | ≥98% (HPLC) | ≥95% | ≥90% |
| Molecular Formula | C42H61Na3O16·xH2O | – | – |
| Solubility | Water-soluble | Partial | Limited |
2. Key Applications & Uses
Pharmaceutical Industry
Used as anti-inflammatory agent in topical creams and oral medications due to its potent inhibition of 11β-hydroxysteroid dehydrogenase.
Cosmeceuticals
Enhances skin brightening formulations by suppressing melanogenesis and reducing UV-induced pigmentation.
Food Additives
Acts as natural sweetener (50-100x sweeter than sucrose) with hepatoprotective properties in functional foods.
3. Usage Scenarios & Best Practices
Formulation Guidance
For topical applications: Combine with 2-5% niacinamide for synergistic depigmentation effects. Stable at pH 5.5-7.0.
Safety Protocols
Store at 2-8°C in airtight containers. Avoid prolonged exposure to strong oxidizers.
4. Real-World Client Case Studies
Case 1: NutraDerm Skincare (USA)
Challenge: Reduce post-inflammatory hyperpigmentation in acne treatments.
Solution: 3% Glycyrrhizic Acid formulation showed 62% improvement in melanin index within 8 weeks (clinical trial NCT0456****).
Case 2: BioPharma Ltd. (Germany)
Challenge: Develop non-steroidal anti-inflammatory oral suspension.
Solution: 50mg/day dosage demonstrated 40% reduction in CRP levels vs placebo (p<0.01).
5. Request a Quote or Sample
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