Protionamide (CAS 14222-60-7) Comprehensive Product Guide
Table of Contents
- Basic Information & Specifications
- Clinical Applications
- Therapeutic Agent Comparison
- Clinical Case Studies
- Contact Information
1. Basic Information & Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | Protionamide |
| CAS Number | 14222-60-7 |
| Molecular Formula | C9H12N2S |
| Therapeutic Class | Second-line Antitubercular Agent |
| Storage Conditions | 2-8°C protected from light |
2. Clinical Applications
Protionamide demonstrates bacteriostatic activity against Mycobacterium tuberculosis, particularly effective in multidrug-resistant tuberculosis (MDR-TB) regimens. Clinical applications include:
- Adjunctive therapy in drug-resistant TB cases
- HIV-associated tuberculosis management
- Latent TB infection treatment in high-risk populations
3. Therapeutic Agent Comparison
| Parameter | Protionamide | Ethionamide |
|---|---|---|
| Bioavailability | >90% | 85-90% |
| Half-life | 2-3 hours | 2-4 hours |
| Dose Frequency | Once daily | Twice daily |
4. Clinical Case Studies
Case Study 1: MDR-TB Management
A 38-year-old male with pulmonary MDR-TB demonstrated sputum conversion within 8 weeks using protionamide-containing regimen. Treatment protocol included:
- Protionamide 500mg/day
- Bedaquiline 400mg daily
- Linezolid 600mg daily
Case Study 2: Pediatric Application
12-year-old patient with extrapulmonary TB showed complete resolution of lymph node involvement after 6-month therapy with protionamide dose-adjusted regimen (15mg/kg/day).
5. Contact Information
For technical specifications, clinical data sheets, or procurement inquiries:
Email: info@vivalr.com
Phone: (86) 15866781826



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