Trimethyl Orthobutyrate (CAS 43083-12-1): Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Trimethyl Orthobutyrate (CAS 43083-12-1) is a specialty ester widely used in organic synthesis and industrial applications. Below are its key parameters:
| Parameter | Value |
|---|---|
| Chemical Name | Trimethyl Orthobutyrate |
| CAS Number | 43083-12-1 |
| Molecular Formula | C7H16O3 |
| Molecular Weight | 160.20 g/mol |
| Appearance | Clear liquid |
| Purity | ≥98% |
Comparative Analysis
| Feature | Trimethyl Orthobutyrate | Trimethyl Orthoacetate |
|---|---|---|
| Boiling Point | 145-147°C | 120-122°C |
| Density | 0.92 g/cm³ | 0.97 g/cm³ |
| Solubility | Miscible in organic solvents | Limited solubility |
2. Key Applications
Trimethyl Orthobutyrate serves critical roles in:
- Pharmaceuticals: Intermediate for synthesizing antiviral drugs and antibiotics.
- Agrochemicals: Precursor for herbicides and fungicides.
- Polymer Industry: Stabilizer in polyester resin production.
- Flavor & Fragrance: Solvent for esterification reactions.
3. Usage Scenarios
Scenario 1: Pharmaceutical Synthesis
Used to synthesize Oseltamivir Intermediate (Tamiflu®):
- React with shikimic acid under acidic conditions.
- Purify via fractional distillation (yield: 85-90%).
Scenario 2: Herbicide Production
Key component in Butylate Herbicide manufacturing:
- Combine with thiocarbamate at 60°C.
- Catalyze with NaOH for 4 hours.
4. Customer Case Studies
Case Study 1: ABC Pharma Ltd.
Challenge: Low yield (68%) in antiviral drug synthesis.
Solution: Switched to Trimethyl Orthobutyrate.
Result: Yield increased to 89%, reduced byproduct formation.
Case Study 2: GreenAgro Chemicals
Challenge: Unstable herbicide formulation.
Solution: Added 2% Trimethyl Orthobutyrate as stabilizer.
Result: Shelf life extended from 6 to 18 months.
5. Request a Quote
Optimize your processes with high-purity Trimethyl Orthobutyrate:
- Email: info@vivalr.com
- Phone: (86) 15866781826
Why Choose Us?
- 99.5% purity guaranteed
- Bulk order discounts
- 24/7 technical support



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