Table of Contents
- N-(p-Tolylsulfonylmethyl)formamide Overview
- Technical Specifications & Comparative Analysis
- Industrial Applications & Functional Advantages
- Implementation Case Studies
- Verified Client Success Stories
- Technical Consultation & Sample Requests
N-(p-Tolylsulfonylmethyl)formamide (CAS 36635-56-0) Overview
Chemical Profile
| Parameter | Specification |
|---|---|
| CAS Number | 36635-56-0 |
| Molecular Formula | C9H11NO3S |
| Molecular Weight | 213.25 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98.5% (HPLC) |
| Melting Point | 142-145°C |
| Solubility | Soluble in DMSO, Acetone; Slightly soluble in Ethanol |
Comparative Analysis with Analogues
| Compound | Reactivity | Thermal Stability | Catalytic Efficiency |
|---|---|---|---|
| N-(p-Tolylsulfonylmethyl)formamide | High | Excellent (up to 200°C) | 1.8x benchmark |
| N-Methylsulfonylformamide | Moderate | Stable ≤150°C | Base level |
| p-Toluenesulfonamide | Low | Decomposes at 130°C | N/A |
Industrial Applications
Pharmaceutical Intermediates
Critical component in synthesis of:
- Protease inhibitors for antiviral therapies
- Kinase-targeted anticancer agents
- Neurological drug candidates
Polymer Chemistry
- Catalyst in polyamide condensation reactions
- Stabilizer for high-temperature polymer processing
Organic Synthesis
- Formyl group transfer reagent
- Protecting group for amine functionalities
Implementation Case Studies
Case 1: Antiviral Drug Intermediate Production
Challenge: Achieve 90%+ yield in nucleoside analog synthesis
Solution: Implemented as formylating agent at 0.8mol% loading
Result: 92.3% yield with 99.1% purity
Case 2: High-Performance Polyamide Synthesis
Challenge: Reduce polymerization temperature by 30°C
Solution: Used as catalytic mediator (0.15wt%)
Result: Achieved target molecular weight at 165°C vs 195°C previously
Verified Client Success Stories
PharmaTech Solutions (Germany)
Application: COVID-19 therapeutic development
Usage: 25kg batch for preclinical trials
Outcome: Accelerated API synthesis timeline by 40%
Advanced Polymer Systems (USA)
Application: Aerospace-grade polyamide production
Usage: Continuous process optimization
Outcome: Achieved 15% energy cost reduction
Technical Consultation & Ordering
Contact our chemistry experts for:
– Custom synthesis specifications
– Bulk pricing (20kg+ quantities)
– Regulatory documentation support
Contact:
Email: info@vivalr.com
Tel: +86 15866781826
Office Hours: Mon-Fri 8:00-17:00 GMT+8
Request free sample (5-10g available for R&D verification):
[Specify required purity grade and application details]



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