Polyglutamic Acid Cas 25513-46-6

Appearance: White powder
Assay: 99.0% to 100.5%
Packing: 25kg/drum
Sample: Available

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Table of Contents

Polyglutamic Acid (CAS 25513-46-6) Overview

Key Specifications

Parameter γ-PGA Hyaluronic Acid Collagen
Molecular Weight 10k-2,000k Da 50k-3,000k Da 300k Da
Moisture Retention 5x HA Capacity Baseline 1.2x HA
Biodegradability Full Partial Low
pH Stability 3-12 6-8 5-7.5

Advantages in Industrial Use

  • Superior water-binding capacity: 1g binds 5,000g water
  • Non-animal origin: Fermentation-derived (Bacillus subtilis)
  • ECOCERT/COSMOS certified for cosmetics

Industrial & Commercial Applications

Cosmetic Formulations

Moisturizing serums (0.5-2% concentration), anti-aging creams (synergistic with retinol), pH-balancing toners.

Biomedical Uses

Drug delivery matrices (sustained release up to 72hr), wound healing hydrogels (FDA 510(k)-cleared devices).

Agricultural Solutions

Fertilizer additive (15-30% NPK utilization increase), drought-resistance inducer in crops.

Implementation Guidelines

Cosmetic Manufacturing Protocol

  1. Hydrate γ-PGA in deionized water (30min, 40°C)
  2. Blend with actives at <50°C to preserve integrity
  3. Adjust pH to 5.5-6.5 before emulsification

Pharmaceutical Compatibility

Drug Type Loading Efficiency Release Profile
Small Molecules 92-97% 24-48hr linear
Peptides 85-90% 72hr sustained

Documented Client Successes

Case 1: LuxeDerm Skincare (France)

  • Challenge: Reduce HA content while boosting hydration
  • Solution: 1.8% γ-PGA serum formulation
  • Result: 63% TEWL reduction vs. previous HA-based product

Case 2: AgriGrow Solutions (USA)

  • Challenge: Improve corn yield in drought conditions
  • Solution: 0.05% γ-PGA foliar spray
  • Result: 22% yield increase vs. control group

Technical & Commercial Inquiry

Request formulation guidance or MSDS documentation:

Include: Application sector, required purity (Cosmetic/Pharma/Industrial Grade), and target quantity.

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