Table of Contents
- Product Overview
- Applications of Polyglutamic Acid
- Usage Cases & Best Practices
- Client Case Studies
- Contact for Technical Consultation
Polyglutamic Acid (CAS 25513-46-6) Overview
Key Specifications
| Parameter | γ-PGA | Hyaluronic Acid | Collagen |
|---|---|---|---|
| Molecular Weight | 10k-2,000k Da | 50k-3,000k Da | 300k Da |
| Moisture Retention | 5x HA Capacity | Baseline | 1.2x HA |
| Biodegradability | Full | Partial | Low |
| pH Stability | 3-12 | 6-8 | 5-7.5 |
Advantages in Industrial Use
- Superior water-binding capacity: 1g binds 5,000g water
- Non-animal origin: Fermentation-derived (Bacillus subtilis)
- ECOCERT/COSMOS certified for cosmetics
Industrial & Commercial Applications
Cosmetic Formulations
Moisturizing serums (0.5-2% concentration), anti-aging creams (synergistic with retinol), pH-balancing toners.
Biomedical Uses
Drug delivery matrices (sustained release up to 72hr), wound healing hydrogels (FDA 510(k)-cleared devices).
Agricultural Solutions
Fertilizer additive (15-30% NPK utilization increase), drought-resistance inducer in crops.
Implementation Guidelines
Cosmetic Manufacturing Protocol
- Hydrate γ-PGA in deionized water (30min, 40°C)
- Blend with actives at <50°C to preserve integrity
- Adjust pH to 5.5-6.5 before emulsification
Pharmaceutical Compatibility
| Drug Type | Loading Efficiency | Release Profile |
|---|---|---|
| Small Molecules | 92-97% | 24-48hr linear |
| Peptides | 85-90% | 72hr sustained |
Documented Client Successes
Case 1: LuxeDerm Skincare (France)
- Challenge: Reduce HA content while boosting hydration
- Solution: 1.8% γ-PGA serum formulation
- Result: 63% TEWL reduction vs. previous HA-based product
Case 2: AgriGrow Solutions (USA)
- Challenge: Improve corn yield in drought conditions
- Solution: 0.05% γ-PGA foliar spray
- Result: 22% yield increase vs. control group
Technical & Commercial Inquiry
Request formulation guidance or MSDS documentation:
- Email: info@vivalr.com
- Tel: (86) 15866781826
Include: Application sector, required purity (Cosmetic/Pharma/Industrial Grade), and target quantity.



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