2,2,2-Trifluoroethylamine CAS 753-90-2

Chemical Name: 2,2,2-Trifluoroethylamine
CAS No.: 753-90-2
Molecular Formula: C2H4F3N
Molecular weight: 99.06

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2,2,2-Trifluoroethylamine (CAS 753-90-2) Ultimate User Guide

Table of Contents

1. Product Overview & Key Parameters

Parameter Specification
CAS Number 753-90-2
Molecular Formula C2H4F3N
Purity Grade ≥99% (Pharmaceutical Grade)
Boiling Point 48-50°C at 760 mmHg
Flash Point -15°C (Closed Cup)
Storage Conditions 2-8°C in inert atmosphere

2. Industrial Applications & Use Cases

Pharmaceutical Intermediate

Critical component in synthesizing:

  • Fluorinated antidepressant APIs
  • PET imaging contrast agents
  • Protease inhibitor building blocks

Agrochemical Synthesis

Key fluorine source for:

  • Next-gen herbicides (e.g., trifluoromethyl-containing compounds)
  • Systemic insecticide formulations

3. Comparative Analysis with Similar Compounds

Compound Reactivity Thermal Stability Cost Efficiency
2,2,2-Trifluoroethylamine High Moderate ★★★★☆
Trifluoroethylamine HCl Moderate High ★★★☆☆
Pentafluoroethylamine Low High ★★☆☆☆

4. Step-by-Step Usage Guidelines

  1. Pre-cool reaction vessel to -20°C
  2. Use anhydrous solvents (THF/DMF recommended)
  3. Maintain pH between 6.5-7.5 during reactions
  4. Employ slow addition technique for exothermic control

5. Real-World Client Success Stories

Case 1: Anticancer Drug Development

Client: Top 10 Global Pharma Company

Challenge: Improve drug molecule metabolic stability

Solution: Incorporated 2,2,2-Trifluoroethylamine in lead compound

Outcome: 40% increase in half-life during preclinical trials

Case 2: Advanced Insecticide Formulation

Client: EU Agrochem Manufacturer

Challenge: Develop low-toxicity pest control agent

Solution: Used as key fluorination agent in novel synthesis route

Outcome: Achieved EPA approval 6 months ahead of schedule

6. Technical Consultation & Ordering

Our fluorine chemistry experts provide:

  • Custom synthesis protocols
  • Regulatory compliance support
  • Bulk pricing (100kg+ orders)

Contact our team for technical specifications:

✉️ Email: info@vivalr.com
Tel: (86) 15866781826

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