HATU 99.5% CAS 148893-10-1: Ultimate User Guide
Table of Contents
- Product Overview
- Key Applications
- Parameter Comparison
- Usage Guidelines
- Case Studies
- Contact for Technical Support
Product Overview
HATU (Hexafluorophosphate Azabenzotriazole Tetramethyl Uronium) is a premium peptide coupling reagent with 99.5% purity (CAS 148893-10-1). Key specifications:
| Parameter | Value |
|---|---|
| Molecular Weight | 380.23 g/mol |
| Appearance | White crystalline powder |
| Solubility | DMSO, DMF, Acetonitrile |
| Storage | 2-8°C in dry environment |
Key Applications
HATU 99.5% excels in:
- Solid-phase peptide synthesis (SPPS)
- Amide bond formation in complex organic molecules
- Nucleic acid conjugate preparation
- Pharmaceutical intermediate synthesis
Parameter Comparison
| Reagent | Coupling Efficiency | Reaction Time | Side Products |
|---|---|---|---|
| HATU | 98.7% | 15-30 min | Low |
| HBTU | 95.2% | 30-45 min | Moderate |
| EDC | 89.5% | 60-90 min | High |
Usage Guidelines
Optimal Reaction Conditions
- Use anhydrous DMF/DMSO as solvent
- Maintain 0.1-0.3M concentration
- React at 0-25°C under inert gas
Case Studies
Case 1: Peptide Drug Development
Client: EuroPharma Solutions (Germany)
Application: Synthesized 32-mer antimicrobial peptide
Result: 89% yield improvement vs HBTU
Case 2: Cancer Research
Client: OncoResearch Institute (USA)
Application: Developed PD-1/PD-L1 inhibitor conjugates
Result: Reduced racemization by 72%
Contact for Technical Support
For bulk orders or technical specifications:
Email: info@vivalr.com
Tel: (86) 15866781826



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