HATU 99.5% CAS 148893-10-1

Assay: 99.5%min
Appearance: White Crystalline powder
Capacity: 300MT per year
Packaging: 25kg/carton drum or aluminium foil bag
Sample: available

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HATU 99.5% CAS 148893-10-1: Ultimate User Guide

Table of Contents

Product Overview

HATU (Hexafluorophosphate Azabenzotriazole Tetramethyl Uronium) is a premium peptide coupling reagent with 99.5% purity (CAS 148893-10-1). Key specifications:

Parameter Value
Molecular Weight 380.23 g/mol
Appearance White crystalline powder
Solubility DMSO, DMF, Acetonitrile
Storage 2-8°C in dry environment

Key Applications

HATU 99.5% excels in:

  • Solid-phase peptide synthesis (SPPS)
  • Amide bond formation in complex organic molecules
  • Nucleic acid conjugate preparation
  • Pharmaceutical intermediate synthesis

Parameter Comparison

Reagent Coupling Efficiency Reaction Time Side Products
HATU 98.7% 15-30 min Low
HBTU 95.2% 30-45 min Moderate
EDC 89.5% 60-90 min High

Usage Guidelines

Optimal Reaction Conditions

  1. Use anhydrous DMF/DMSO as solvent
  2. Maintain 0.1-0.3M concentration
  3. React at 0-25°C under inert gas

Case Studies

Case 1: Peptide Drug Development

Client: EuroPharma Solutions (Germany)
Application: Synthesized 32-mer antimicrobial peptide
Result: 89% yield improvement vs HBTU

Case 2: Cancer Research

Client: OncoResearch Institute (USA)
Application: Developed PD-1/PD-L1 inhibitor conjugates
Result: Reduced racemization by 72%

Contact for Technical Support

For bulk orders or technical specifications:
Email: info@vivalr.com
Tel: (86) 15866781826

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