pyridine hydrochloride cas 628-13-7

Assay: 98.5%min
Appearance: White crystalline powder
Packing: 5kg plastic bucket,25kg carton
Sample: Available

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Pyridine Hydrochloride (CAS 628-13-7) Ultimate User Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter Pyridine Hydrochloride Pyridine Morpholine HCl
CAS Number 628-13-7 110-86-1 100-24-3
Molecular Formula C5H6ClN C5H5N C4H10ClNO
Appearance White crystalline powder Colorless liquid White crystals
Application Superiority Enhanced solubility in polar solvents
Stable acidic catalyst
Limited protonation capability Lower nucleophilicity

2. Comprehensive Applications

Pharmaceutical Intermediate

Critical component in synthesizing antihistamines and vitamin B3 derivatives. Enables precise pH control during quinolone antibiotic production.

Organic Synthesis

Superior catalyst for:
– Friedel-Crafts acylations
– Knoevenagel condensations
– Peptide coupling reactions

Analytical Chemistry

Mobile phase modifier in HPLC separation of basic compounds. Reduces peak tailing by 40-60% compared to standard pyridine.

3. Implementation Case Studies

Case 1: Antiviral Drug Synthesis

Challenge: Low yield (48%) in rimantadine hydrochloride synthesis
Solution: Implemented 0.5 mol% Pyridine HCl as proton sponge
Result: Yield increased to 82% with 99.2% purity

Case 2: Polymer Production

Challenge: Inconsistent molecular weight in polyamide synthesis
Solution: Used 1.2 eq Pyridine HCl as acid scavenger
Result: Achieved Mw 15,000 ± 500 Da consistency

4. Verified Client Success Stories

PharmaTech Solutions (Germany)

Application: Cephalosporin intermediate purification
Metrics: Reduced purification steps from 5 to 3
Outcome: 30% cost reduction per batch

UniChem Research (USA)

Application: Heterocyclic compound alkylation
Metrics: Reaction time decreased from 18h to 6h
Outcome: 200% lab productivity improvement

5. Technical Consultation & Quotation

Request customized technical support or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826

Why Choose Our Product?

  • ISO 9001-certified production
  • Batch-to-batch consistency: >99.5% purity
  • Global logistics: DHL/FedEx certified hazardous materials handling
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