diacetonefructose cas 20880-92-6

Assay(HPLC): NLT 98.0% and NMT 102.0%
Appearance: White to off-white powder
Packing: 25kg/Fiber Drum
Sample: Available

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Diacetonefructose (CAS 20880-92-6): Comprehensive Technical Guide

1. Key Specifications & Comparative Analysis

Parameter Diacetonefructose Conventional Sugar Derivatives
CAS Number 20880-92-6 N/A
Molecular Formula C12H20O6 Variable
Molecular Weight 260.28 g/mol 180-400 g/mol
Melting Point 94-95°C 80-150°C
Boiling Point 332.6±37.0°C 200-350°C
Solubility Chloroform, Methanol, Ethyl Acetate Polar Solvents

2. Industrial Applications

Diacetonefructose serves as a critical intermediate in pharmaceutical synthesis, particularly for anticonvulsant drugs like Topiramate. Its ketone-protected structure enhances stability during multi-step organic reactions. Key functional advantages include:

  • High chiral purity (>99%) for enantioselective synthesis
  • Thermal stability up to 300°C
  • Low hygroscopicity compared to unprotected sugars

3. Functional Use Cases

Pharmaceutical Synthesis

In Topiramate production, Diacetonefructose undergoes sulfamation followed by ammonolysis to create the drug’s core bicyclic structure. Process benefits:

  • Yield improvement: 72% → 89%
  • Purity enhancement: <95% → >99.5%
  • Reaction time reduction: 18h → 9h

4. Client Implementation Examples

Case Study 1: Shenzhen Xingkaiyue Biotechnology

Application: Bulk API production
Scale: 25 MT/month
Results: Achieved 99.99% HPLC purity through optimized crystallization protocols.

Case Study 2: Xi’an Qicheng Fine Chemicals

Application: Antiepileptic drug intermediates
Scale: 10 MT/month
Results: Reduced production costs by 22% via solvent recycling systems.

5. Procurement Inquiry

For technical specifications, MSDS, or bulk pricing:

Email: info@vivalr.com
Tel: (86) 15866781826

Global shipping available with COA and stability data.

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