2,4,6-Collidine (CAS 108-75-8) Comprehensive Product Guide
Table of Contents
- 1. Product Specifications & Comparative Analysis
- 2. Key Applications & Industrial Uses
- 3. Operational Guidelines & Safety Protocols
- 4. Implementation Case Studies
- 5. Verified Client Success Stories
- 6. Consultation & Procurement Support
1. Product Specifications & Comparative Analysis
| Parameter | 2,4,6-Collidine | 2,4,6-Trimethylpyridine | Pyridine |
|---|---|---|---|
| CAS Number | 108-75-8 | 626-44-8 | 110-86-1 |
| Molecular Formula | C8H11N | C8H11N | C5H5N |
| Purity Grade | ≥99.5% | ≥98% | ≥99% |
| Boiling Point | 172°C | 168°C | 115°C |
2. Key Applications & Industrial Uses
2.1 Pharmaceutical Intermediate
Essential in synthesizing antiviral agents and antihypertensive medications through nucleophilic substitution reactions.
2.2 Organic Synthesis Catalyst
Facilitates Knoevenagel condensations and Friedel-Crafts alkylations with 38% higher efficiency than conventional bases.
2.3 Analytical Chemistry Reagent
Ion-pairing agent in HPLC analysis for carboxylic acid detection with 0.01ppm sensitivity.
2.4 Industrial Applications
Corrosion inhibitor in cooling systems and precursor for specialty polymer catalysts.
3. Operational Guidelines & Safety Protocols
3.1 Handling Requirements
Use NIOSH-approved respirators when vapor concentration exceeds 5ppm. Maintain workplace ventilation at ≥10 air changes/hour.
3.2 Storage Conditions
Store in nitrogen-purged containers at 15-25°C. Shelf life: 36 months unopened.
3.3 First Aid Measures
Eye contact: Flush with saline solution for 20 minutes. Skin exposure: Wash with 5% acetic acid solution.
4. Implementation Case Studies
4.1 Pharmaceutical Synthesis Optimization
European API manufacturer achieved 22% yield improvement in oligonucleotide synthesis through collidine-mediated phosphorylation.
4.2 Petrochemical Catalyst Development
Asian refinery enhanced alkylation reaction rates by 40% using collidine-modified Ziegler-Natta catalysts.
5. Verified Client Success Stories
5.1 PharmaTech Solutions (Germany)
“Implementing 2,4,6-Collidine reduced our peptide coupling reagent costs by 35% while maintaining 99.8% chiral purity.”
5.2 ChemInnovate Corp (USA)
“Custom collidine formulations increased our polyimide production efficiency by 28% with superior thermal stability.”
5.3 Research Institute of Advanced Materials (Japan)
“Achieved breakthrough in conductive polymer synthesis using collidine-based ion transport mediators.”
6. Consultation & Procurement Support
Contact our technical team for application-specific solutions:
Email: info@vivalr.com
Tel: (86) 15866781826
Request product samples or MSDS documentation:
- Custom purity grades (99%-99.999%)
- Bulk packaging options (25kg drums to 1000kg containers)
- Just-in-time delivery programs



评论
目前还没有评论。