O-Cresolphthalein (CAS 596-27-0) Comprehensive User Guide
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Industrial Uses
- 3. Performance Comparison with Similar Indicators
- 4. Operational Guidelines & Best Practices
- 5. Real-World Application Cases
- 6. Technical Support & Purchasing Assistance
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 596-27-0 |
| Chemical Formula | C22H18O4 |
| Molecular Weight | 346.38 g/mol |
| Appearance | White to pink crystalline powder |
| Melting Point | 223-226°C |
| Solubility | Soluble in ethanol, acetone; insoluble in water |
| pH Range | 8.2 (colorless) to 9.8 (purple-red) |
| Storage | 2-8°C in airtight container |
2. Key Applications & Industrial Uses
Primary Functions:
- pH-sensitive colorimetric indicator in alkaline solutions
- Metallochromic indicator for calcium determination
- Endpoint detection in complexometric titrations
Industry-Specific Applications:
| Industry | Application |
|---|---|
| Clinical Diagnostics | Serum calcium quantification in automated analyzers |
| Water Treatment | Hardness determination in municipal water systems |
| Pharmaceuticals | Quality control of calcium-containing medications |
| Research Laboratories | Metal ion detection in biochemical studies |
3. Performance Comparison with Similar Indicators
| Indicator | pH Range | Metal Specificity | Color Change | Stability |
|---|---|---|---|---|
| O-Cresolphthalein | 8.2-9.8 | Calcium selective | Colorless→Purple-red | High |
| Phenolphthalein | 8.3-10.0 | Non-specific | Colorless→Pink | Moderate |
| Eriochrome Black T | 7.0-11.0 | Multi-metal | Blue→Red | Low |
4. Operational Guidelines & Best Practices
Recommended Protocols:
- Prepare 0.1% (w/v) solution in 95% ethanol
- Use at concentration of 0.01-0.05% in final solution
- Maintain pH between 8.5-10 for optimal performance
- Store working solutions in amber glassware
5. Real-World Application Cases
Case Study 1: Clinical Laboratory Automation
Client: Major European Hospital Network
Application: Automated calcium analysis in 12,000+ monthly blood samples
Result: 99.2% correlation with reference methods, 30% reagent cost reduction
Case Study 2: Industrial Water Analysis
Client: Asian Water Authority
Application: Monitoring calcium hardness in treatment plants
Result: Achieved 0.2 mg/L detection limit, compliant with WHO standards
Case Study 3: Pharmaceutical QC
Client: US-Based Drug Manufacturer
Application: Calcium content verification in antacid production
Result: Reduced batch rejection rate from 5% to 0.8% annually
6. Technical Support & Purchasing Assistance
For technical specifications sheets or bulk pricing inquiries:
Email: info@vivalr.com
Phone: (86) 15866781826
Request custom formulation or discuss application-specific requirements with our chemical engineers. ISO 9001-certified manufacturing with batch-to-batch consistency guaranteed.
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