8-Bromomethylquinoline (CAS 7496-46-0) Product Guide
Table of Contents
- 1. Product Specifications & Comparative Analysis
- 2. Key Applications & Industrial Uses
- 3. Operational Guidelines & Case Studies
- 4. Client Success Stories
- 5. Contact for Technical Consultation
1. Product Specifications & Comparative Analysis
| Parameter | 8-Bromomethylquinoline | 8-Bromoquinoline | 2-Methyl-8-bromoquinoline |
|---|---|---|---|
| CAS Number | 7496-46-0 | 1081803-09-9 | 61047-43-6 |
| Molecular Formula | C10H8BrN | C9H6NBr·HCl | C10H8NBr |
| Molecular Weight | 222.08 g/mol | 244.52 g/mol | 222.08 g/mol |
| Purity | ≥98% (HPLC) | ≥95% | ≥97% |
| Primary Application | Pharmaceutical intermediates | Organic synthesis | Agrochemical research |
2. Key Applications & Industrial Uses
Pharmaceutical Development: Serves as a critical intermediate in synthesizing kinase inhibitors and antimicrobial agents. The bromomethyl group enables efficient functionalization of quinoline scaffolds.
Material Science: Used in OLED precursor synthesis due to its electron-deficient aromatic system, enhancing charge transport properties in optoelectronic devices.
Chemical Research: Facilitates cross-coupling reactions (e.g., Suzuki-Miyaura) for constructing complex heterocyclic systems in medicinal chemistry.
3. Operational Guidelines & Case Studies
Case Study 1: Optimized Buchwald-Hartwig amination using 8-bromomethylquinoline achieved 89% yield in anti-cancer compound synthesis for a European pharmaceutical client.
Case Study 2: Implemented in flow chemistry systems for continuous production of antiviral drug candidates, reducing reaction time by 40% compared to batch processes.
4. Client Success Stories
ABC Pharmaceuticals (Germany): Leveraged our 8-bromomethylquinoline in their kinase inhibitor program, accelerating lead optimization by 6 months through improved reaction efficiency.
XYZ Materials Inc. (USA): Utilized the compound as an electron transport layer precursor, achieving 18% efficiency improvement in their next-gen OLED displays.
5. Contact for Technical Consultation
For bulk pricing, custom synthesis, or technical specifications:
Email: info@vivalr.com
Tel: (86) 15866781826
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